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Scaffold-free 3D cell culture of primary skin fibroblasts induces profound changes of the matrisome
A virus-free nanoparticle–3D scaffold platform for efficient human iPSC reprogramming and differentiation
Xeno-Free Biomimetic-Scaffold Supports hiPSC-Derived Dental Organoid Formation and Tooth Regeneration
A virus-free nanoparticle–3D scaffold platform for efficient human iPSC reprogramming and differentiation [WTC0011 RNA-Seq]
Human induced pluripotent stem cells (hiPSCs) hold substantial promise for regenerative medicine and cell manufacturing, yet their widespread adoption remains limited by reprogramming strategies that are inefficient, costly, unsafe, and difficult to scale, driven by reliance on viral vectors, limite...
ORGANISM(S): Homo sapiens 
2026-02-18 | GSE319038 | GEO
Aspiration-assisted intra-operative 3D bioprinting of scaffold-free modular units for skeletal muscle tissue regeneration
Scaffold-free cryopreservable cartilage grafts obtained from hiPSC-derived chondroprogenitor cells for airway reconstruction with growth adaptability
Tooth regeneration remains an unmet clinical challenge due to the structural complexity of dental tissues and the requirement for precise epithelial–mesenchymal interactions during development. Here, we present a xeno-free, biomimetic strategy for dental organoid engineering by integrating human ind...
ORGANISM(S): Homo sapiens 
2026-02-18 | GSE319198 | GEO
The study of muscle dystrophies, including Duchenne and Myotonic dystrophies, has faced significant challenges due to the lack of physiologically relevant in vitro models. This research introduces a novel, scaffold- and biomaterial-free platform based on cell sheet engineering to create in vitro mod...
ORGANISM(S): Homo sapiens (Human) 
2024-12-24 | PXD052728 | Pride
Traumatic muscle injury associated with volumetric muscle loss results in reversible muscle regeneration and function. Bottlenecks to conventional tissue engineering strategies to augment muscle regeneration are limited by low cell transplantation capacity by conventional injection of dissociated ce...
ORGANISM(S): Homo sapiens Mus musculus 
2025-05-31 | GSE292577 | GEO
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