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ProteomicsPhosphorylation of CENP-A on serine 7 does not control centromere function
CENP-A is the histone H3 variant necessary to specify the location of all eukaryoticcentromeres via its CENP-A targeting domain and either one of its terminal regions. In humans, several post-translational modifications occur on CENP-A, but their role in centromere function remains controversial. On...
ORGANISM(S): Homo sapiens (Human) 
2019-01-28 | PXD012163 | Pride
Centromere Phosphorilation Cenp-a Cell cycle 
GenomicsPolycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity
These data include the genome wide location of different histone modifications by ChIP sequencing in mouse ES cells, and RNA Seq data generated from wild type and EED KO mouse ES cells and knocked down for unrelated protein and Setd2 protein. ChIP-Seq: Immuno-precipitation of formaldehyde cross-lin...
ORGANISM(S): Mus musculus 
2013-12-05 | E-GEOD-51006 | biostudies-arrayexpress
GenomicsOgt chromatin recruitment is mediated by TET proteins in mouse ES cells [ChIP-Seq]
These data include the genome wide location analysis of Ogt by ChIP of Ogt in mouse ES cells. Precipitation of formaldehyde cross-linked chromatin prepared from mouse ES cell using specific antibody against OGT and IgG as control.
ORGANISM(S): Mus musculus 
2013-01-06 | E-GEOD-39154 | biostudies-arrayexpress
TranscriptomicsOgt chromatin recruitment is mediated by TET proteins in mouse ES cells [expression array]
O-linked N-acetylglucosamine (O-GlcNAc ) transferase (OGT) activity is essential for embryonic stem (ES) cell viability and mouse development. OGT is present in both cytoplasm and nucleus of different cell types and mediates serine or threonine glycosylation. The Ogt gene locus resides on the X-chro...
ORGANISM(S): Mus musculus 
2013-01-06 | E-GEOD-39321 | biostudies-arrayexpress
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