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UnknownFunctional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities.
Not available
S-EPMC6561742 | biostudies-literature
ProteomicsPhosphorylation of CENP-A on serine 7 does not control centromere function
CENP-A is the histone H3 variant necessary to specify the location of all eukaryoticcentromeres via its CENP-A targeting domain and either one of its terminal regions. In humans, several post-translational modifications occur on CENP-A, but their role in centromere function remains controversial. On...
ORGANISM(S): Homo sapiens (Human) 
2019-01-28 | PXD012163 | Pride
Centromere Phosphorilation Cenp-a Cell cycle 
GenomicsPolycomb-dependent H3K27me1 and H3K27me2 regulate active transcription and enhancer fidelity
These data include the genome wide location of different histone modifications by ChIP sequencing in mouse ES cells, and RNA Seq data generated from wild type and EED KO mouse ES cells and knocked down for unrelated protein and Setd2 protein. ChIP-Seq: Immuno-precipitation of formaldehyde cross-lin...
ORGANISM(S): Mus musculus 
2013-12-05 | E-GEOD-51006 | biostudies-arrayexpress
TranscriptomicsSILENCING OF PNPLA6, THE NEUROPATHY TARGET ESTERASE (NTE) CODIFYING GENE, ALTERS HUMAN NEURODIFFERENTIATION IN VITRO
Neuropathy Target Esterase (NTE) is a protein involved in the development of a polyneuropathy caused by exposure to certain organophosphorus compounds. In vivo and in vitro studies have also associated NTE with embryonic development since NTE null mice embryos are non-viable, and silencing the NTE-c...
ORGANISM(S): Homo sapiens 
2014-10-06 | E-GEOD-55761 | biostudies-arrayexpress
GenomicsOgt chromatin recruitment is mediated by TET proteins in mouse ES cells [ChIP-Seq]
These data include the genome wide location analysis of Ogt by ChIP of Ogt in mouse ES cells. Precipitation of formaldehyde cross-linked chromatin prepared from mouse ES cell using specific antibody against OGT and IgG as control.
ORGANISM(S): Mus musculus 
2013-01-06 | E-GEOD-39154 | biostudies-arrayexpress
UnknownGenomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox.
Not available
S-EPMC3907846 | biostudies-literature
UnknownA novel self-lipid antigen targets human T cells against CD1c(+) leukemias.
Not available
S-EPMC4076585 | biostudies-literature
GenomicsMaintenance of Leukemic Cell Identity by the Activity of the Polycomb Complex PRC1 (ChIP-seq)
These data include the genome wide occupancy of H2AUbq by ChIP sequencing in Cdkn2a-/- Lin- HSC cells non-transduced or transduced with MLL-AF9, HOXA9 and PML-RARa. Immuno-precipitation of formaldehyde cross-linked chromatin prepared from Cdkn2a-/- Lin- HSC cells non-transduced or transduced with ML...
ORGANISM(S): Mus musculus 
2016-10-21 | E-GEOD-67498 | biostudies-arrayexpress
UnknownFam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.
Not available
S-EPMC5538769 | biostudies-literature
TranscriptomicsMaintenance of Leukemic Cell Identity by the Activity of the Polycomb Complex PRC1 (RNA-seq)
These data include RNA Seq data generated from Ring1b wild type and Ring1b KO Ring1a-/- Cdkn2a-/- Lin- HSC cells non-transduced or transduced with MLL-AF9, HOXA9 and PML-RARa. Total RNA extracted from Ring1b wild type and Ring1b KO Ring1a-/- Cdkn2a-/- Lin- HSC cells non-transduced or transduced wit...
ORGANISM(S): Mus musculus 
2016-10-21 | E-GEOD-67517 | biostudies-arrayexpress
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