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UnknownNeuronal signal-regulatory protein alpha drives microglial phagocytosis by limiting microglial interaction with CD47 in the retina.
Not available
S-EPMC9772037 | biostudies-literature
TranscriptomicsTranscription profiling of rat fibroblasts transformed with HRAS and treated with the demethylating agent 5-aza-2-deoxycytidine
Silencing of gene expression by methylation of CpG islands in regulatory elements is frequently observed in cancer. However, an influence of the most common oncogenic signalling pathways onto DNA methylation has not yet been investigated thoroughly. To address this issue, we identified genes suppres...
ORGANISM(S): Rattus norvegicus 
2007-11-06 | E-GEOD-4427 | biostudies-arrayexpress
UnknownEffects of aspirin plus extended-release dipyridamole versus clopidogrel and telmisartan on disability and cognitive function after recurrent stroke in patients with ischaemic stroke in the Prevention Regimen for Effectively Avoiding Second Strokes (PRoFESS) trial: a double-blind, active and placebo-controlled study.
Not available
S-EPMC2772657 | biostudies-literature
ProteomicsTMT proteomic analysis of PFN1 iPSC-microglia
To compare the proteome between PFN1 mutant and PFN1 WT iPSC-microglia under baseline conditions
ORGANISM(S): Homo sapiens (Human) 
2024-02-18 | PXD038943 | Pride
Human Als Microglia Profilin 1 
TranscriptomicsWhole genome expression profile of lung epithelial cells following chronic arsenic exposure
This study chronically exposed human lung epithelial BEAS-2B cells to low-dose arsenic trioxide in vitro to elucidate cancer promoting gene signaling networks (GSNs) associated with As-transformed (B-As) cells. Following a six month exposure, exposed cells were assessed for enhanced cell proliferat...
ORGANISM(S): Homo sapiens 
2012-09-26 | E-GEOD-33520 | biostudies-arrayexpress
UnknownSerial Analysis of Gene Mutations and Gene Expression during First-Line Chemotherapy against Metastatic Colorectal Cancer: Identification of Potentially Actionable Targets within the Multicenter Prospective Biomarker Study REVEAL.
Not available
S-EPMC9367450 | biostudies-literature
UnknownA lymphocyte-microglia-astrocyte axis in chronic active multiple sclerosis.
Not available
S-EPMC8719282 | biostudies-literature
ProteomicsPlaque induced transcriptional reprogramming of microglia towards lymphoid receptor expression protects against Alzheimer's disease
Microglia, the innate immune cells of the brain, play a defining role in the progression of Alzheimer’s disease (AD). The microglial response to amyloid plaques can be either neuroprotective or neurotoxic. Here we show that the protective function of microglia is associated with and functionally lin...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-07 | PXD063383 | Pride
Alzheimer's Microglia Lc-ms/ms 
UnknownExpression of ALS-PFN1 impairs vesicular degradation in iPSC-derived microglia.
Not available
S-EPMC10954694 | biostudies-literature
UnknownLymphoid gene expression supports neuroprotective microglia function.
Not available
S-EPMC12675299 | biostudies-literature
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