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ProteomicsCritical Assessment of Metaproteome Investigation (CAMPI): a Multi-Lab Comparison of Established Workflows
Metaproteomics, the study of the collective proteome within a microbial ecosystem, has substantially grown over the past few years. This growth comes from the increased awareness that it can powerfully supplement metagenomics and metatranscriptomics analyses. Although metaproteomics is more challeng...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2022-02-16 | PXD023217 | Pride
Microbial communities Metaproteomics Multi-omics 
UnknownA Robust and Universal Metaproteomics Workflow for Research Studies and Routine Diagnostics Within 24 h Using Phenol Extraction, FASP Digest, and the MetaProteomeAnalyzer.
Not available
S-EPMC6707425 | biostudies-literature
ProteomicsFecal metaproteomics reveals reduced gut inflammation and changed microbial metabolism following lifestyle-induced weight loss
Aims Gut microbiota-mediated inflammation promotes obesity-associated low-grade inflammation, which represents a hallmark of the metabolic syndrome (MetS). Lifestyle-induced weight loss (WL) is regarded as an efficient therapy to reverse MetS and to prevent disease progression. The objective of this...
ORGANISM(S): human gut metagenome 
2021-04-19 | PXD020902 | Pride
Metaproteomics Obesity Metabolic syndrome Microbiome Gut inflammation Weight loss 
ProteomicsMetaproteomics of fecal samples supports the diagnosis of Crohn’s Disease and Ulcerative Colitis
Objective Crohn’s Disease (CD) and Ulcerative Colitis (UC) are chronic inflammatory diseases of the gastrointestinal tract. Reliable diagnosis of these diseases requires a comprehensive examination of the patient, which include invasive endoscopy. This study assesses whether non-invasive LC-MS/MS ba...
ORGANISM(S): Homo sapiens (Human) 
2019-03-11 | PXD010371 | Pride
• fecal samples • metaproteomics • non-invasive diagnosis • inflammatory bowel disease • crohn’s disease • ulcerative colitis • gastrointestinal tract 
ProteomicsNo evidence for major spacial differences within the microbial communities in anaerobic digestion plants under different feeding and stirring regimes
In anaerobic digestion plants (ADP) homogenization of the feed, the fermenter content and the microbial communities represents a precondition for effective and robust biogas production,but also a major energy consumer. For a 850 m3 agricultural AD-P equipped with eight sampling ports we investigated...
ORGANISM(S): Escherichia coli 
2021-04-27 | PXD016213 | Pride
Microbial communities Stirring Trflp Anaerobic digestion  biogas Metaproteomics 
ProteomicsDiscovering biomarkers for non-alcoholic steatohepatitis pa-tients with and without hepatocellular carcinoma using fecal metaproteomics
High-calorie diets lead hepatic steatosis and to the development of non-alcoholic fatty liver disease (NAFLD), which can evolve over many years into the inflammatory form non-alcoholic steatohepatits (NASH) posing a risk for the development of hepatocellular carcinoma (HCC). Due to the diet and the ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD034175 | Pride
Non-alcoholic steatohepatitis Metaproteomics Hepatocellular carcinoma Fecal microbiota Ma-chine learning 
ProteomicsHuman stool (IBD patients, LC-MS/MS)
Fecal samples (n=52) of a cohort of IBD patients were collected before and after 14 weeks of treatment with three different biologics. Clinical disease activity scores were used to determine the clinical response and remission. Fecal metaproteomes of remitting patients (n=12) and of non-remitting pa...
ORGANISM(S): human gut metagenome 
2026-03-20 | PXD053257 | Pride
Human Ibd Stool Lc-ms/ms 
ProteomicsCritical Assessment of Metaproteome Investigation (CAMPI): a Multi-Lab Comparison of Established Workflows
Metaproteomics, the study of the collective proteome within a microbial ecosystem, has substantially grown over the past few years. This growth comes from the increased awareness that it can powerfully supplement metagenomics and metatranscriptomics analyses. Although metaproteomics is more challeng...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) Homo Sapiens (ncbitaxon:9606) 
2022-06-08 | MSV000089620 | MassIVE
UnknownCritical Assessment of MetaProteome Investigation (CAMPI): a multi-laboratory comparison of established workflows.
Not available
S-EPMC8674281 | biostudies-literature
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