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The deposited data concern the mapping of acetylation sites on wild-type and the K280A, Y363A mutants of Elp3 by LC-MS/MS. Abstract of the manuscript: tRNA modifications affect ribosomal elongation speed and co-translational folding dynamics. The Elongator complex is responsible for introducing 5-ca...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
Transcription profiling by array of the compound U0126 in PC3 prostate cancer cells
ORGANISM(S): Homo sapiens 
We performed gene expression profiling of 31 breast cell lines (BCL) using whole-genome DNA microarrays (Affymetrix U133+2.0) to assessed a better molecular characterization of breast cell lines in order to help discover of new markers to apply to tumour samples.
ORGANISM(S): Homo sapiens 
ELMOD2 cDNA from the IMAGE clone 3897166 was cloned into the pDsRed-Monomer-N1 expression vector. ELMOD2 was overexpressed in the A549(adenomcarcinoma)cell line and cells transfected with empty vector were considered controls. Transcript profiles were compared with the Affymetrix Hgu133plus2 arrays....
ORGANISM(S): Homo sapiens 
Sixteen pre-treatment samples of pathologically confirmed solitary fibrous tumors (SFT) were available for RNA profiling. They were collected from 16 patients who underwent initial surgery and/or diagnostic biopsy. Samples were macrodissected by pathologists, and frozen within 30 min of removal in l...
ORGANISM(S): Homo sapiens 
Various mutations in the rpoB gene, which encodes the RNA polymerase beta subunit, are associated with increased vancomycin (VAN) resistance in vancomycin-intermediate S. aureus (VISA) and hetero-VISA (hVISA) strains. We reported that rpoB mutations are also linked to the expression of the recently ...
ORGANISM(S): Staphylococcus aureus 
hVISA clinical strain Mu3 spontaneously generates VISA at an extremely high frequency (1x10-6 or greater) within its cell population. The VISA-converted mutant strains generally grow slower than their parent hVISA strain, but they usually form colonies on vancomycin-containing agar plates after 48 h...
ORGANISM(S): Staphylococcus aureus 
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