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UnknownCirculating microRNA expression profiles associated with systemic lupus erythematosus.
Not available
S-EPMC6662589 | biostudies-literature
TranscriptomicsAffymetrix expression data from colon cancer patient tissues
Gene expression profiling of 111 colon tissues from tumors and adjacent noncancerous tissues. Genotypes for the rs5995355 in NCF4 are included to identify genes whose expression are associated with this genotype. RNA from fresh frozen colon tissues were extracted using Trizol and hybridized to Affym...
ORGANISM(S): Homo sapiens 
2014-02-19 | E-GEOD-44861 | biostudies-arrayexpress
TranscriptomicsMicroRNAs altered in colon adenomas
95 microRNA probes were found to have altered expression in colon adenomas compared to paired non-adenoma tissue Total mRNA was extracted from colon tissue that was flash frozen immediately after surgery. A total of 36 tissues were used for microarray analysis. Briefly, 5 ug of RNA were biotin lab...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-29915 | biostudies-arrayexpress
TranscriptomicsThe rectal cancer microRNAome - a comprehensive comparative analysis of microRNA expression in rectal cancer and matched normal mucosa
Purpose: MicroRNAs play a prominent role in a variety of physiological and pathological biological processes, including cancer. For rectal cancers, only limited data are available on microRNA expression profiles, while the underlying genomic and transcriptomic aberrations have been firmly establishe...
ORGANISM(S): Homo sapiens 
2012-10-05 | E-GEOD-38389 | biostudies-arrayexpress
TranscriptomicsAssociation of microRNAs with CD68 and NOS2 in IBD tissues.
We analyzed the association of CD68 and NOS2 mRNA expression with microRNAs in IBD tissues. For this analysis, data was LOESS normalized in R. Data was then imported into Partek Genomics Suite and Batch effects caused by day to day variability (Dategroup of array charateristic) were corrected. We...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-29703 | biostudies-arrayexpress
TranscriptomicsAssociation of microRNAs with colon tumor metastases
We compared the expression of microRNAs in primary colon tumors with their paired liver metastases using the Nanostring human microRNA assays version 1 23 microRNAs were found to be differentially expressed between colon primary tumors and their paired metastases Total mRNA was extracted from flash ...
ORGANISM(S): Homo sapiens 
2014-08-01 | E-GEOD-44121 | biostudies-arrayexpress
TranscriptomicsMiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer from never-smokers
Approximately 15% of lung cancer cases are not associated with smoking and show molecular and clinical characteristics distinct from those in smokers. Epidermal growth factor receptor (EGFR) gene mutations, which are correlated with sensitivity to EGFR-tyrosine kinase inhibitors (EGFR-TKIs), are mo...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-14936 | biostudies-arrayexpress
TranscriptomicsThe impact of calorie restriction and diet-induced obesity on microRNA expression
We analyzed the impact of calorie restriction and diet-induced obesity on expression of microRNAs in the mouse colon. For this analysis, data was LOESS normalized in R. Data was then imported into BRB Array for analysis. We identified microRNAs that were altered in response to calorie-restriction ...
ORGANISM(S): Mus musculus 
2014-04-30 | E-GEOD-56025 | biostudies-arrayexpress
TranscriptomicsPaired non-cancerous and cancerous miRNA expression of esophageal adenocarcinoma and squamous cell carcinoma patients
Identifying biomarkers predictive for early esophageal cancer detection is critical considering the dismal survival rates. We investigated the involvement of microRNAs (miRNAs), their utility as biomarkers, and their association with survival in esophageal cancer, including Barrett’s associated and...
ORGANISM(S): Homo sapiens 
2010-07-09 | E-GEOD-13937 | biostudies-arrayexpress
TranscriptomicsmicroRNA Expression Profiling of MIF-high and MIF-low Pancreatic Ductal Adenocarcinoma using Nanostring nCounter Platform
We identified differentially expressed microRNAs between MIF-high and MIF-low tumor groups. These microRNAs were then investigated for their potential downstream targets using an integrative strategy, which combines miR-Walk target prediction module and mRNA expression array data to identify key MIF...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-62498 | biostudies-arrayexpress
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