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UnknownRear 4-min Schirmer test, a modified indicator of Schirmer test in diagnosing dry eye.
Not available
S-EPMC9012812 | biostudies-literature
ProteomicsInvestigation of inter- and intra-day variability of tear fluid regarding flow rate, protein concentration as well as protein composition
Purpose: Determination of inter- and intra-day variations in tear flow rate, tear fluid protein concentration as well as protein composition regarding their impact for future biomarker studies.Methods: Tear fluid was collected non-invasively from 18 healthy subjects performing Schirmer tests at four...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD037811 | Pride
Mass spectrometry Tear fluid Schirmer test Tear flow rate  tear volume Protein concentration 
UnknownTear production as measured by Schirmer tear test-1 in dogs with atopic dermatitis.
Not available
S-EPMC12477742 | biostudies-literature
UnknownImmunophenotyping in Vernal Keratoconjunctivitis: Schirmer Test for Therapy Response Prediction.
Not available
S-EPMC12261867 | biostudies-literature
ProteomicsEffect of acupuncture on tear proteomics in patients with video display terminal-related dry eye
In our study, the tear proteome was compared with identify possible mechanisms and biomarkers for predicting acupuncture effectiveness in VDT-related dry eye. The results showed that the Ocular Surface Disease Index (OSDI) scores were significantly different between the acupuncture group (AC group) ...
ORGANISM(S): Homo Sapiens 
PXD051759 |
MetabolomicsTear lipidomics profiling reveals ocular-surface lipid remodeling associated with organelle stress in a mouse model of inflammatory dry eye disease
This study aimed to determine whether dry eye disease (DED) is accompanied by ocular-surface lipid remodeling and whether such changes converge on organelle stress–associated pathways in a mouse model of inflammatory dry eye. Tear samples were collected from mice and analyzed by LC–MS/MS–based non-t...
2026-04-04 | MTBLS14217 | MetaboLights
MetabolomicsTear lipidomics profiling reveals inflammatory dry eye disease-associated lipid metabolic remodeling at the ocular surface
This study aimed to investigate whether inflammatory dry eye disease (DED) is accompanied by abnormal lipid metabolic remodeling at the ocular surface. Tear samples were collected from patients with DED and matched healthy controls. Lipidomics profiling was performed using LC–MS/MS with a standardiz...
2026-04-03 | MTBLS14218 | MetaboLights
ProteomicsDeficiency of Antioxidant Enzyme PRDX6 and Mucosal Chemokine CXCL17: Unraveling the Factors Behind Oxidative Stress and Mucosal Homeostasis Disruption in Dry Eye Disease
This study aimed to identify dysregulated proteins, signaling pathways, and biological processes on the ocular surface of patients with Sjögren’s syndrome dry eye (SSDE) disease. Non-targeted proteomic analysis of Schirmer strip (ScS) samples from 12 SSDE patients compared to 6 healthy subjects (HS)...
ORGANISM(S): Homo sapiens (Human) 
2025-07-25 | PXD051945 | Pride
Tear film Signaling pathways Cxcl17 Prdx6 Cytoskeleton Biomarker Dry eye disease Sjögren’s syndrome Timstof pro Lc-ms/ms 
UnknownPre-test characteristics of unstable angina patients with obstructive coronary artery disease confirmed by coronary angiography.
Not available
S-EPMC6241968 | biostudies-literature
TranscriptomicsCirculating Mononuclear Cell Transcriptomes in Patients with Atherosclerotic Coronary Artery Disease
Monocytes and T-cells play an important role in the development of atherosclerotic coronary artery disease (CAD). Differences in transcriptional activity of these cells might reflect the individual's atherosclerotic burden. Transcriptome analysis of circulating mononuclear cells from carefully match...
ORGANISM(S): Homo sapiens 
2008-12-01 | E-GEOD-9820 | biostudies-arrayexpress
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