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Schistosomiasis is a parasitic zoonosis which caused by schistosomes and poses great threat to the health of human and other mammals. Schistosome cercaria must penetrate skin as an initial step to successfully infect the final host. Proteolytic enzymes secreted from the acetabular glands of cercaria...
ORGANISM(S): Caenorhabditis elegans 
2017-05-08 | PXD002185 | Pride
HDACs inhibitors induces mortality in the parasite Schistosoma mansoni (schistosomula and adult worms), and became an interesting drug class for the development of new drugs to treat schistosomiasis. In order to understand the effect of histone hyperacetylation on the parasite, we tested the effect ...
ORGANISM(S): Schistosoma mansoni 
2017-01-31 | GSE83209 | GEO
HDACs inhibitors induces mortality in the parasite Schistosoma mansoni (schistosomula and adult worms), and became an interesting drug class for the development of new drugs to treat schistosomiasis. In order to understand the effect of histone hyperacetylation on the parasite, we tested the effect ...
ORGANISM(S): Schistosoma mansoni 
2017-01-31 | GSE83208 | GEO
HDACs inhibitors induces mortality in the parasite Schistosoma mansoni (schistosomula and adult worms), and became an interesting drug class for the development of new drugs to treat schistosomiasis. In order to understand the effect of histone hyperacetylation on the parasite, we tested the effect ...
ORGANISM(S): Schistosoma mansoni 
2017-01-31 | GSE83210 | GEO
Schistosoma mansoni is the major causative agent of schistosomiasis in the Americas. This parasite takes advantage from host signaling molecules such as cytokines and hormones to complete its development inside the host. TNF-α is the most important cytokine involved in the inflammatory response whe...
ORGANISM(S): Schistosoma mansoni 
Migrating schistosomula are an important stage of the schistosome lifecycle and represent a key target for elimination of infection by natural and vaccine induced host immune responses. To gain a better understanding of how these parasites initiate a primary host immune response we have characterise...
ORGANISM(S): Mus musculus 
2011-02-10 | GSE27171 | GEO
Schistosomula exposed to HDAC inhibitor (Trichostatin A)
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