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TranscriptomicsTranscription profiling of 80 Arabidopsis tissues/cells (AtGenExpress data) see also E-TABM-17 for a re-annotated set with CEL files for download
The activity of genes and their encoded products can be regulated in several ways, but transcription is the primary level, since all other modes of regulation (RNA splicing, RNA and protein stability, etc.) are dependent on a gene being transcribed in the first place. The importance of transcription...
ORGANISM(S): Arabidopsis thaliana 
2022-11-20 | E-AFMX-9 | biostudies-arrayexpress
TranscriptomicsmiRseq Analysis of Human Macrophages Co-cultured with MCF-7 Breast Cancer Cells
Tumor-immune cell interactions shape the immune cell phenotype, with microRNAs (miRs) being crucial components of this crosstalk. How they are transferred, and how they affect their target landscape, especially in tumor-associated macrophages (TAMs), is largely unknown. Here we aimed to define miRo...
ORGANISM(S): Homo sapiens 
2019-02-08 | E-MTAB-6885 | biostudies-arrayexpress
UnknownEffectiveness of Nifurtimox Eflornithine Combination Therapy (NECT) in T. b. gambiense second stage sleeping sickness patients in the Democratic Republic of Congo: Report from a field study.
Not available
S-EPMC8601604 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidosis Ler and Cvi ecotypes and 17 derived inbred recombinant lines subjected to micro-landscape fragmentation and two levels of disturbance revealing functional landscape genomics reveals genetic changes in fixed and migrating experimental populations.
We carried out a five-generation selection experiment in which two Arabidopsis accessions (Ler and Cvi) and 17 Recombinant Inbred Lines (RILs) derived from them were subjected in 24 replicated populations to four levels of micro-landscape fragmentation and two levels of disturbance, factorially cros...
ORGANISM(S): Arabidopsis thaliana 
2010-05-12 | E-MTAB-107 | biostudies-arrayexpress
ProteomicsKinase inhibition sensitizes pancreatic cancer cells towards radiation
Pancreatic ductal adenocarcinoma is one of the most aggressive cancer types and is well-known for its general low intrinsic radiosensitivity. In order to resolve mechanisms of how PDAC cells carry out radioresistance, a combination of proteomics and phosphoproteomics of two radiosensitive as well as...
ORGANISM(S): Mus musculus (Mouse) 
2020-07-13 | PXD015284 | Pride
Pdac Phosphoproteomics Pancreatic cancer 
UnknownThe four weeks before lockdown during the COVID-19 pandemic in Germany: a weekly serial cross-sectional survey on risk perceptions, knowledge, public trust and behaviour, 3 to 25 March 2020.
Not available
S-EPMC8532505 | biostudies-literature
UnknownRbpj expression in regulatory T cells is critical for restraining TH2 responses.
Not available
S-EPMC6453958 | biostudies-literature
TranscriptomicsIdentification of translationally deregulated proteins during inflammation
The regulation of translation is crucial for cells to rapidly adapt to changing conditions. Although the transcriptional changes under inflammatory conditions are intensely studied, not much is known about translational changes. Therefore, this study aimed at identifying translationally deregulated ...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-35022 | biostudies-arrayexpress
ProteomicsEndothelial Glycocalyx Injury in Obstructive Sleep Apnea Links Repetitive Hypoxemia to Immunothrombotic Endothelial Dysfunction
BACKGROUND: Obstructive sleep apnea (OSA) is associated with cardiovascular disease. The endothelial glycocalyx (eGCX) is a shear-sensitive, interfacial barrier towards the intravascular compartment. The relevance of OSA and intermittent hypoxia (IH) for eGCX injury and, subsequently, cardiovascular...
ORGANISM(S): Homo sapiens (Human) 
2026-06-29 | PXD073409 | Pride
Plasma proteomics Neat plasma 
GenomicsSelection of epigenetic variation in Arabidopsis [SNP data]
In Arabidopsis thaliana a high rate of spontaneous epigenetic variation can occur in the DNA methylome in the absence of genetic variation and selection. It has been of great interest, whether natural epigenetic variation is subject to selection and contributes to fitness and adaptation in selective...
ORGANISM(S): Arabidopsis thaliana 
2014-09-01 | E-GEOD-47490 | biostudies-arrayexpress
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