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MetabolomicsPolyamines regulate adaptive antitumor immunity by functional specialization of regulatory T cells

In cancer, metabolic changes and uncontrolled tumor growth alter nutrient availability, impacting antitumor immune responses. Regulatory T (Treg) cells are a subset of T cells with immunosuppressive properties that has been found to additionally possess the ability to control tissue homeostasis a...

2025-07-24 | MTBLS12633 | MetaboLights
UnknownStimulated plasmacytoid dendritic cells impair human T-cell development.
Not available
S-EPMC1895464 | biostudies-literature
ProteomicsEffect of POR knockdown on the proteome of HepaRG cells
Cytochrome P450 oxidoreductase (POR) is involved in the oxidative metabolism of xenobiotics and endogenous compounds like fatty acid and cholesterol. While effects of diminished Por were extensively studied in mouse models, studies in human models are still missing. We used previously established CR...
ORGANISM(S): Homo sapiens (Human) 
2021-11-04 | PXD028577 | Pride
Proteomics Heparg Bile acid metabolism Crispr/cas9 Cholesterol biosynthesis Nadph cytochrome p450 reductase 
UnknownPeriodontal bacterial supernatants modify differentiation, migration and inflammatory cytokine expression in human periodontal ligament stem cells.
Not available
S-EPMC6609032 | biostudies-literature
UnknownMetabolic changes during periodontitis therapy assessed by real-time ambient mass spectrometry.
Not available
S-EPMC8669448 | biostudies-literature
UnknownNew frontiers in esophageal radiology.
Not available
S-EPMC8184422 | biostudies-literature
UnknownHigh-Throughput Assessment of Kinome-wide Activation States.
Not available
S-EPMC6838672 | biostudies-literature
UnknownMR1-ligand cross-linking identifies vitamin B6 metabolites as TCR-reactive antigens.
Not available
S-EPMC12461623 | biostudies-literature
UnknownImage-guided video-assisted thoracoscopic resection (iVATS): Translation to clinical practice-real-world experience.
Not available
S-EPMC7383497 | biostudies-literature
UnknownStructural changes to monomeric CuZn superoxide dismutase caused by the familial amyotrophic lateral sclerosis-associated mutation A4V.
Not available
S-EPMC2749781 | biostudies-literature
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