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MetabolomicsImproving global feature detectabilities through scan range splitting for untargeted metabolomics by high-performance liquid chromatography-Orbitrap mass spectrometry
Untargeted metabolomics aims at obtaining quantitative information on the highest possible number of low-molecular biomolecules present in a biological sample. Rather small changes in mass spectrometric spectrum acquisition parameters may have a significant influence on the detectabilities of metabo...
2016-06-09 | MTBLS233 | MetaboLights
ProteomicsHUVEC 3xHA.FoxO3.A3.ER +4-OHT vs vector +4-OHT
Forkhead Box O (FoxO) transcription factors are conserved proteins involved in the regulation of life span and age-related diseases, such as diabetes and cancer. Stress stimuli or growth factor deprivation promote nuclear localization and activation of FoxO proteins, which - depending on the cellula...
ORGANISM(S): Homo sapiens (Human) 
2022-01-20 | PXD027615 | Pride
Endothelium Foxo3 Human Huvec 
ProteomicsMachine Learning Based Classification of Diffuse Large B-cell Lymphoma Patients by their Protein Expression Profiles
Characterization of tumors at the molecular level has improved our knowledge of cancer causation and progression. Proteomic analysis of their signaling pathways promises to enhance our understanding of cancer aberrations at the functional level, but this requires accurate and robust tools. Here, we ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-30 | MSV000080813 | MassIVE
OtherMachine Learning Based Classification of Diffuse Large B-cell Lymphoma Patients by their Protein Expression Profiles.
Data from ProteomeXchange, PXD ID: PXD002052. Experiment: TRR37, file: folder summary. Published as part of Mol Cell Proteomics. 2015 Aug 26 . From the Abstract: {{i}} ... Here, we develop a state of the art quantitative mass spectrometric pipeline to characterize formalin-fixed paraffin-embedded (...
ORGANISM(S): Homo_sapiens_viruses, Human 
GPM32320017943 | GPMDB
Resource Reanalysis 
ProteomicsAbsolute protein quantification of Mycoplasma pneumoniae proteome by combining selected reaction monitoring of a reduced set of labeled peptides and label-free shotgun mass spectrometry.
We quantified the protein abundances of Mycoplasma pneumoniae (Mpn), a genome-reduced organism, by combining selected reaction monitoring of a reduced set of labeled peptides and label-free shotgun mass spectrometry. A set of 77 labeled peptides were synthesized and used as internal standard peptide...
ORGANISM(S): Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
2023-08-31 | PXD035159 | Pride
Mycoplasma pneumoniae Absolute quantification Label-free Selected reaction monitoring 
TranscriptomicsContinuous T cell receptor signals maintain a functional regulatory T cell pool
During development, thymocytes bearing a moderately self-reactive T cell receptor (TCR) can be selected to become regulatory T (Treg) cells. Several observations suggest that also in the periphery mature Treg cells continuously receive self-reactive TCR signals. However, the importance of this inhe...
ORGANISM(S): Mus musculus 
2014-10-21 | E-GEOD-62532 | biostudies-arrayexpress
UnknownInsight into the Molecular Signature of Skeletal Muscle Characterizing Lifelong Football Players.
Not available
S-EPMC9740844 | biostudies-literature
UnknownUse of stable isotope ratio analysis to investigate the biology and clinical significance of seal parasites.
Not available
S-EPMC11474010 | biostudies-literature
TranscriptomicsEpigenomic landscapes of human inflammation associated macrophages [RNA-seq]
We previously demonstrated by genomic and bioinformatical approaches that human macrophage (MΦ) activation is best described by a spectrum model (Xue et al, Immunity, 2014). MΦ integrate exogenous input signals on transcriptional level in a unique fashion to generate specific functional programs, ...
ORGANISM(S): Homo sapiens 
2016-02-28 | E-GEOD-66593 | biostudies-arrayexpress
TranscriptomicsCell-type specific transcriptome analysis to study germline development and reproduction in apomictic Boechera gunnisoniana- ATH1 arrays
Apomixis differs from sexual reproduction only in three major aspects: While the sexual megaspore mother cell undergoes meiosis, the apomictic initial cell omits or aborts meiosis (apomeiosis); the unreduced egg cell of apomicts forms an embryo without fertilization (parthenogenesis), and formation ...
ORGANISM(S): Boechera gunnisoniana 
2014-06-01 | E-GEOD-51996 | biostudies-arrayexpress
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