Untargeted metabolomics aims at obtaining quantitative information on the highest possible number of low-molecular biomolecules present in a biological sample. Rather small changes in mass spectrometric spectrum acquisition parameters may have a significant influence on the detectabilities of metabo...
Data from ProteomeXchange, PXD ID: PXD001685. File: B08-07165_c.mzml. Published as part of J Proteome Res. 2015 Jun 5 . From the Abstract: {{i} ... Eighty breast tumors, stratified for estrogen receptor status and development of distant recurrence (DR - ), were collected. After enrichment of N-glyc...
We aimed to identify gene variants associated with heart failure by using a rat model of the human disease. We performed invasive cardiac hemodynamic measurements in F2 crosses between spontaneously hypertensive heart failure rats (SHHF) and reference strains. We combined linkage analyses with genom...
Beneficial effects of long-chain omega-3 polyunsaturated fatty acids (n-3 FAs) are generally well-known from epidemiological studies, but the various mechanisms of action are not completely clarified. Regulation of gene expression is one known mechanism of action, but only very limited data of regul...
