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GenomicNEIGHBOR Consortium Glaucoma GWAS

This is a case-control study of primary open angle glaucoma (POAG). POAG is an intraocular pressure (IOP) related progressive optic neuropathy that ultimately leads to blindness. For this study we have formed a collaborative consortium contributing 2170 POAG cases and 2347 controls with a unified...

phs000238 | dbGaP
TranscriptomicsChromatin immunoprecipitation of transcription factor Dpf3 in mouse myoblast cells (C2C12) to identify genome wide binding sites
The aim of the experiment was to identify genome wide binding sites for the transcription factor Dpf3 by using Chromatin Immunoprecipitation followed by microarray analysis (ChIP-chip) in C2C12 cells.
ORGANISM(S): Mus musculus 
2008-08-01 | E-TABM-362 | biostudies-arrayexpress
TranscriptomicsA New Class of Homoserine Lactone Quorum Sensing Signals
Quorum sensing is a term used to describe cell-to-cell communication that allows cell density-dependent gene expression. Many Gram-negative bacteria use acyl-homoserine lactone (acyl-HSL) synthases to generate fatty acyl-HSL quorum sensing signals, which function with signal receptors to control exp...
ORGANISM(S): Rhodopseudomonas palustris CGA009 
2010-05-25 | E-GEOD-10642 | biostudies-arrayexpress
MetabolomicsMetabolomic Profiling of Renal Cyst Fluid in Advanced ADPKD: Insights from Dialysis and Transplantation Cohorts

Background: Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disorder characterized by progressive renal cyst formation, often leading to end-stage kidney disease (ESKD). While urinary metabolomics in ADPKD has been extensively studied, the composition of renal cyst fluid, par...

2025-07-07 | MTBLS12372 | MetaboLights
UnknownRIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation.
Not available
S-EPMC6375735 | biostudies-literature
ProteomicsTargeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Human genome-wide association studies (GWAS) suggest a functional role for central glutamate receptor signaling and plasticity in body weight regulation. Here, we utilize UK Biobank GWAS summary statistics of body mass index (BMI) and body fat percentage (BF%) to identify genes encoding for proteins...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-16 | PXD047515 | Pride
Weight-loss Brain 
UnknownTargeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment.
Not available
S-EPMC10906926 | biostudies-literature
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