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UnknownEvidence for sequenced molecular evolution of IDH1 mutant glioblastoma from a distinct cell of origin.
Not available
S-EPMC3236649 | biostudies-literature
GenomicsGrhl3 is essential for epidermal barrier repair from both physical and immune injury, relevance to lesional skin disease
Epidermal barrier repair mechanisms activated in psoriasis lesions are likely involved in limiting the severity of this disease. We show that loss of grainyhead-like 3 (Grhl3), a pro-terminal differentiation factor in the epidermis, is sufficient to trigger greater sensitivity to and delayed resolut...
ORGANISM(S): Mus musculus 
2014-09-01 | E-GEOD-52648 | biostudies-arrayexpress
ProteomicsA quantitative model for macrophage activation predicts tunable distance thresholds for propagation of inflammationes in response LPS stimulation
Label free analysis of the secretome of RAW264.7 murine macrophages in response to LPS stimulation.
ORGANISM(S): Mus musculus (Mouse) 
2015-11-30 | PXD001905 | Pride
Lps Raw264.7 murine macrophages Label free Secretome 
MetabolomicsProtozoal populations drive system-wide variation in the rumen microbiome

While rapid progress has been made to characterize the bacterial and archaeal populations of the rumen microbiome, insight into how they interact with keystone protozoal species remains elusive. Here, we reveal two distinct rumen community types (RCT-A and RCT-B) that are not strongly associated ...

2025-06-11 | MTBLS12283 | MetaboLights
UnknownA Method to Deliver Automated and Tailored Intervention Content: 24-month Clinical Trial.
Not available
S-EPMC9490532 | biostudies-literature
UnknownDifferential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine Stimulation.
Not available
S-EPMC4640872 | biostudies-literature
ProteomicsCD209L/L-SIGN N-Glycosylation and N-Glycosylation Site Occupancy
CD209L is a membrane glycoprotein with known glycan-binding properties and it also contains 2 N-glycosylation sequons at sites N92 and N361. Treatment with PNGase F in the presence of H218O, which removes N-linked glycans and isotopically labels the formerly-glycosylated site, confirmed that both un...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021309 | Pride
Human cd209l Dc-sign N-glycosylation 
TranscriptomicsGene expression data from FLCN-restored UOK257-2 renal cancer cells
UOK257 cell line was derived from a BHD patient. It harbors a germline mutation in FLCN (c.1285dupC) and LOH. UOK257-2 cells were generated from UOK257 cells by introducing wildtype FLCN using retrovirus. FLCN inactivation induces TFE3 transcriptional activity by increasing its nuclear localization....
ORGANISM(S): Homo sapiens 
2010-10-11 | E-GEOD-23614 | biostudies-arrayexpress
GenomicsCombinatorial transcription factor binding evolution in five placental mammals
Zoo-ChIP: Functional analysis of experimentally determined combinatorial transcription factor binding in multiple mammalian species
ORGANISM(S): Rattus norvegicus 
2014-09-27 | E-MTAB-1509 | biostudies-arrayexpress
TranscriptomicsSpalax galili and Spalax carmeli Placenta Transcriptomes
Placenta transcriptome from two species of Spalax. Associated with the article "Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax." Transcriptome or Gene expression
ORGANISM(S): Spalax carmeli 
2015-05-12 | E-GEOD-68763 | biostudies-arrayexpress
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