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UnknownThe role of histone demethylases in cancer therapy.
Not available
S-EPMC5528348 | biostudies-literature
MetabolomicsTGF-β uncouples glycolysis and inflammation in macrophages and controls the survival during sepsis

The mechanisms by which macrophage metabolism is regulated and the effects of metabolism on diseases remain largely unknown. We show here that TGF-β regulates the glycolysis of macrophages independently of inflammatory cytokine production, and thus affects the survival in experimental sepsis. Spe...

2023-02-17 | MTBLS6886 | MetaboLights
UnknownDevelopment of a Hospital Compounded, Taste-Masked, Temozolomide Oral Suspension and 5-Year Real-Life Experience in Treating Paediatric Patients.
Not available
S-EPMC9146721 | biostudies-literature
TranscriptomicsGene expression profiling of in vitro derived induced and natural FOXP3+ regulatory T cells and ex-iTreg cells in the mouse
Induced Treg (iTreg) cells are essential for tolerance and can be used therapeutically, yet their stability in vivo and mechanisms of suppression are unresolved. Here, we used a treatment model of colitis to examine the role of autologous IL-10 in iTreg cell function. Mice treated with IL-10+/+ iTr...
ORGANISM(S): Mus musculus 
2012-12-06 | E-GEOD-35543 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human regulatory and helper T cells following activation with anti-CD3 and anti-CD28 for 4 and 16 hours
Primary non-expanded human T cell populations were isolated by leukapheresis from 10 healthy donors. Out of each donor > 95% pure CD4-positive Th cell and >95% pure regulatory T cell populations were purified. Two affymetrix exon arrays were hybridized from each donor both populations as resting, no...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-TABM-779 | biostudies-arrayexpress
UnknownCDK9 inhibition as an effective therapy for small cell lung cancer.
Not available
S-EPMC11106072 | biostudies-literature
UnknownDecoding the diagnostic and therapeutic potential of microbiota using pan-body pan-disease microbiomics.
Not available
S-EPMC11427559 | biostudies-literature
UnknownAbatacept Pharmacokinetics and Exposure Response in Patients Hospitalized With COVID-19: A Secondary Analysis of the ACTIV-1 IM Randomized Clinical Trial.
Not available
S-EPMC11046337 | biostudies-literature
UnknownAirway microbiota signals anabolic and catabolic remodeling in the transplanted lung.
Not available
S-EPMC5792246 | biostudies-literature
UnknownProtective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial.
Not available
S-EPMC5410049 | biostudies-literature
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