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ProteomicsMicrobial functionality as affected by experimental warming of a temperate mountain forest soil - a metaproteomics survey
Soils are a huge reservoir of organic C, and the efflux of CO2 from soils is one of the largest fluxes in the global C cycle. Out of all natural environments, soils probably contain the greatest microbial biomass and diversity, which classifies them as one of the most challenging habitats for microb...
ORGANISM(S): uncultured soil microorganism 
2022-03-14 | PXD004428 | Pride
Soil microbial diversity Microbial community functionality Soil warming 
TranscriptomicsThe little elongation complex (LEC) regulates small nuclear RNA transcription
The Eleven-nineteen Lysine-rich Leukemia (ELL)-containing Super Elongation Complex (SEC) containing P-TEFb is a key regulator in the expression of HOX genes in Mixed Lineage Leukemia (MLL)-based leukemia. We have identified an SEC-like complex in Drosophila, as well as a distinct ELL-containing comp...
ORGANISM(S): Drosophila melanogaster 
2011-12-22 | E-GEOD-32120 | biostudies-arrayexpress
TranscriptomicsMicroRNAs in an Experimental Model of Physiologic Left Ventricular Hypertrophy: a Microarray-based Analysis
BACKGROUND - MicroRNAs (miRs) are a class of small non-coding RNAs that regulate gene expression. Transgenic models have proved that a single miR can induce pathological cardiac hypertrophy and failure. The roles of miRs in the genesis of physiologic left ventricular hypertrophy (LVH), however, are ...
ORGANISM(S): Mus musculus 
2014-06-01 | E-GEOD-52278 | biostudies-arrayexpress
TranscriptomicsExpression data from Saccharomyces cerevisiae
In this study we focus on two Saccharomyces cerevisiae strains with varying production of heterologous M-NM-1-amylase and we compare the metabolic fluxes and transcriptional regulation at aerobic and anaerobic conditions, in particular with the objective to identify the final electron acceptor for p...
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-17 | E-GEOD-38848 | biostudies-arrayexpress
TranscriptomicsmRNA-seq of L1 larvae recovering from arrest
We used RNA-seq to sequence the transcriptome of worms arrested in the first larval stage after hatching without food and starved for 12 hours, then a timecourse of animals recovering from arrest after feeding. We collected samples after 12 hours of starvation and 1, 3 and 6 hours after feeding. Fou...
ORGANISM(S): Caenorhabditis elegans 
2012-04-25 | E-GEOD-33023 | biostudies-arrayexpress
MetabolomicsContributions of the Microbiome-Derived Metabolome for Risk Assessment and Prognostication of Pancreatic Cancer

BACKGROUND Increasing evidence implicates microbiome involvement in the development and progression of pancreatic ductal adenocarcinoma (PDAC). Studies suggest that reflux of gut or oral microbiota can lead to colonization in the pancreas, resulting in dysbiosis that culminates ...

2023-08-09 | MTBLS7260 | MetaboLights
TranscriptomicsRNAi profiling of Drosophila after Nipped-B and Rad21 sister chromatid cohesin proteins in Drosophila ML-DmBG3 cells
Effects of Nipped-B and Rad21 sister chromatid cohesin proteins on gene expression data in ML-DmBG3 cells derived from Drosophila melanogaster larval central nervous system; We examined the effects of Nipped-B and Rad21 knockdown on gene expression in BG3 cells using microarrays that measure over 18...
ORGANISM(S): Drosophila melanogaster 
2009-05-27 | E-GEOD-16152 | biostudies-arrayexpress
TranscriptomicsComprehensive assembly and spatio-temporal analysis of the C. elegans 3' UTRome through isolation and sequencing of 3'UTRs in germline-dereived cell types and somatic tissues.
Our computational analyses of sequencing depth and the discovery rates of sequence elements in the 3M-bM-^@M-^YUTR strongly demonstrate that interrogation of the 3M-bM-^@M-^YUTRome in specific tissues and cell types across development will greatly expand the identification of new 3M-bM-^@M-^YUTR iso...
ORGANISM(S): Caenorhabditis elegans 
2011-11-04 | E-GEOD-33431 | biostudies-arrayexpress
TranscriptomicsRNA-binding protein AUF1 promotes myogenesis by regulating MEF2C expression levels
The mammalian RNA-binding protein AUF1 (AU-binding factor 1, also known as heterogeneous nuclear ribonucleoprotein D, hnRNP D) binds to numerous mRNAs and influences their post-transcriptional fate. Given that many AUF1 target mRNAs encode muscle-specific factors, we investigated the function of AU...
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-58259 | biostudies-arrayexpress
UnknownThe N-terminal Helical Region of the Hepatitis C Virus p7 Ion Channel Protein Is Critical for Infectious Virus Production.
Not available
S-EPMC4654572 | biostudies-literature
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