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MetabolomicsMetabolite Profiling of wildtype and overexpression Arabidopsis thaliana
We use metabolite profiles of the model plant Arabidopsis thaliana measured on an UPLC-ESI/QqTOF-MS to evaluate uni- and multivariate statistical analysis of redundant features in compound spectra. Comparison was performed between the wild-type Col-0 and the 90.32 mutant. The mutant is a transposon ...
2015-09-15 | MTBLS169 | MetaboLights
UnknownCharacterization and immunogenicity of a Shigella flexneri 2a O-antigen bioconjugate vaccine candidate.
Not available
S-EPMC6704370 | biostudies-literature
UnknownChoroid plexus enlargement associates with serum neurofilament and predicts relapse-free progression in multiple sclerosis.
Not available
S-EPMC12923943 | biostudies-literature
ProteomicsProteogenomic pathogenesis and classification of acute myeloid leukemia
Acute myeloid leukemia is a clinically and genetically heterogenous disease characterized by bone marrow infiltration with immature leukemic blasts that cause bone marrow failure. Patient age, comorbidities and genomic disease characteristics have a profound impact on patient outcome. Here, we prese...
ORGANISM(S): Homo sapiens (Human) 
2022-03-08 | PXD022894 | Pride
Transcriptome Mitochondria Proteome Acute myeloid leukemia 
ProteomicsProteogenomic pathogenesis and classification of acute myeloid leukemia
Acute myeloid leukemia is a clinically and genetically heterogenous disease characterized by bone marrow infiltration with immature leukemic blasts that cause bone marrow failure. Patient age, comorbidities and genomic disease characteristics have a profound impact on patient outcome. Here, we prese...
ORGANISM(S): Homo sapiens (Human) 
2022-03-08 | PXD023090 | Pride
Supersilac Proteome Aml 
UnknownAlemtuzumab-induced immune phenotype and repertoire changes: implications for secondary autoimmunity.
Not available
S-EPMC9166548 | biostudies-literature
ProteomicsThe Proteogenomic Subtypes of Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is an aggressive blood cancer with poor prognosis. We performed a comprehensive proteogenomic analysis of bone-marrow biopsies from 252 uniformly treated AML patients to elucidate the molecular pathophysiology of AML in order to inform future diagnostic and therapeutic a...
ORGANISM(S): Homo sapiens (Human) 
2022-03-08 | PXD028007 | Pride
Acute myeloid leukemia Healthy controls Proteome Cd34 cells 
ProteomicsProteogenomic pathogenesis and classification of acute myeloid leukemia (Discovery cohort)
Acute myeloid leukemia is a clinically and genetically heterogenous disease characterized by bone marrow infiltration with immature leukemic blasts that cause bone marrow failure. Patient age, comorbidities and genomic disease characteristics have a profound impact on patient outcome. Here, we prese...
ORGANISM(S): Homo sapiens (Human) 
2022-03-08 | PXD023201 | Pride
Aml Dia Label free proteome 
TranscriptomicsSingle-cell RNA-sequencing of primary colorectal cancer tumor tissue and liver metastasis
Primary tumor or liver metastasis biopsies were obtained from colorectal cancer patients and processed for multiplexed single-cell RNA-sequencing.
ORGANISM(S): Homo sapiens 
2026-04-01 | E-MTAB-16583 | biostudies-arrayexpress
TranscriptomicsTimecourse analysis of human colorectal cancer organoids under FOLFIRI chemotherapy
Two human colorectal cancer organoids derived from liver metastasis of the same patient were grown for seven days, then treated with FOLFIRI chemotherapy in vitro and sampled at different timepoints for single-cell RNA-sequencing. Time points include 0 h, 12 h, 24 h, 48 h, 72 h and 120 h on-treatmen...
ORGANISM(S): Homo sapiens 
2026-04-01 | E-MTAB-16836 | biostudies-arrayexpress
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