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UnknownTargeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53-mutant AML cells
Not available
S-SCDT-10_1038-S44321-024-00024-2 | biostudies-other
TranscriptomicsIdentification and successful negotiation of a metabolic checkpoint in direct neuronal reprogramming
Despite the widespread interest in direct neuronal reprogramming, the mechanisms underpinning fate conversion remain largely unknown. Our study revealed a critical time point after which cells either successfully convert into neurons or succumb to cell death. Co-transduction with Bcl-2 greatly impro...
ORGANISM(S): Mus musculus 
2016-06-29 | E-GEOD-70921 | biostudies-arrayexpress
OtherInflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors.
Data from ProteomeXchange, PXD ID: PXD001500. Experiment: IFNAR_KO_Prog_78a, file: 120503_JH_IFNAR_KO_Prog_78a_10.mzml. Published as part of Cell Stem Cell. 2015 Aug 19. pii: S1934-5909(15)00306-9 . From the Abstract: {{i}} ... Here, we report that the phenotypic hematopoietic stem cell (HSC) compa...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32310023393 | GPMDB
Resource Reanalysis 
GenomicsC/EBPa is required for self-renewal, lineage priming and maintenance of epigenetic configurations in hematopoietic stem cells
Transcription factors are key regulators of hematopoieticstem cells (HSCs) and act through their ability to bind DNA andimpact on gene transcription. Their functions are interpreted inthe complex landscape of chromatin but current knowledge on howthis is achieved is very limited. C/EBPa is an import...
ORGANISM(S): Mus musculus 
2013-12-01 | E-GEOD-43007 | biostudies-arrayexpress
UnknownEvaluation of Interventions for Cognitive Symptoms in Long COVID: A Randomized Clinical Trial.
Not available
S-EPMC12603944 | biostudies-literature
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