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UnknownGenomic investigation of Staphylococcus aureus recovered from Gambian women and newborns following an oral dose of intra-partum azithromycin.
Not available
S-EPMC6798832 | biostudies-literature
Unknown<i>In vivo</i> visualization of osteoarthritic hypertrophic lesions.
Not available
S-EPMC6054140 | biostudies-literature
TranscriptomicsTranscription profiling of human neuroblastoma cell line IMR-32 overexpressiong SQSTM1 and DPP3 to identify activators for the antioxidant response element
The antioxidant response element (ARE) is a cis-acting regulatory enhancer element found in the 5’ flanking region of many phase II detoxification enzymes. Upregulation of ARE-dependent target genes is known to have neuroprotective effects; yet, the mechanism of activation is largely unknown. By scr...
ORGANISM(S): Homo sapiens 
2007-11-01 | E-GEOD-6451 | biostudies-arrayexpress
UnknownPIK3CA mutations are associated with decreased benefit to neoadjuvant human epidermal growth factor receptor 2-targeted therapies in breast cancer.
Not available
S-EPMC5087318 | biostudies-literature
ProteomicsMS analysis of photocrosslink adducts for the mapping of interaction sites of selective engineered PSD-95 PDZ domain ligands
Designing highly specific modulators of protein-protein interactions (PPIs) is especially challenging in the context of multiple paralogs and conserved interaction surfaces. In this case, direct generation of selective and competitive inhibitors is hindered by high similarity within the evolutionary...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-11-12 | PXD015366 | Pride
Engineered ligand/pdz domains/photocrosslinking/p-azidophenylalanine 
ProteomicsespL deletion mutant of Mycobacterium tuberculosis
The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellular pathogens. Here, by combining genetic and high-throughput approaches, we show that EspL, a protein of 115 amino acids, is essential for mediating E...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2018-12-10 | PXD010929 | Pride
Mycobacterium Virulence Tuberculosis Espl 
UnknownPrevalence of Venous Thromboembolism and Anticoagulant Use in Patients with COVID-19 in Alberta, Canada.
Not available
S-EPMC9524556 | biostudies-literature
TranscriptomicsAn epithelial integrin regulates the amplitude of protective lung interferon responses
Integrins facilitate intercellular movement and communication. Unlike the promiscuous activities of many integrins, β6 integrin is restricted to epithelia and partners exclusively with integrin αV to modulate acute lung injury (ALI). Given that ALI is a complication of respiratory infection, we us...
ORGANISM(S): Mus musculus 
2016-07-18 | E-GEOD-68802 | biostudies-arrayexpress
UnknownSearch and Contain: Impact of an Integrated Genomic and Epidemiological Surveillance and Response Program for Control of Carbapenemase-producing Enterobacterales.
Not available
S-EPMC8662772 | biostudies-literature
TranscriptomicsA Chondrogenic Molecule that Repairs Cartilage by Transcriptional Regulation of CBF-beta
Osteoarthritis (OA) is a degenerative joint disease that involves destruction of articular cartilage and eventually leads to disability. Mesenchymal stem cells (MSCs) reside in healthy and diseased cartilage, and through their chondrogenic potential may provide a strategy for cartilage repair. To th...
ORGANISM(S): Homo sapiens 
2012-05-01 | E-GEOD-35546 | biostudies-arrayexpress
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