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ProteomicsespL deletion mutant of Mycobacterium tuberculosis
The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellular pathogens. Here, by combining genetic and high-throughput approaches, we show that EspL, a protein of 115 amino acids, is essential for mediating E...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2018-12-10 | PXD010929 | Pride
Mycobacterium Virulence Tuberculosis Espl 
GenomicsTranscriptional profile of Mycobacterium tuberculosis espL deletion mutant
Transcriptional profile of Mycobacterium tuberculosis espL deletion mutant
PRJNA487629 | ENA
TranscriptomicsTranscriptional profile of Mycobacterium tuberculosis espL deletion mutant
The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis. The ESX-1 cluster comprises approximately twenty genes and encodes a specialized secretion apparatus, which releases effectors into the extracellular milieu. The goal of this study is to u...
ORGANISM(S): Mycobacterium tuberculosis 
2018-12-07 | GSE118994 | GEO
UnknownEspL is essential for virulence and stabilizes EspE, EspF and EspH levels in Mycobacterium tuberculosis.
Not available
S-EPMC6319747 | biostudies-literature
UnknownEspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation.
Not available
S-EPMC7613272 | biostudies-literature
ProteomicsMass-spectrometry-based analysis of the secretome of M. tuberculosis mutants
The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellular pathogens. Here we study the proteme of various ESX-1 knock-out mutants.
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2018-12-10 | PXD011466 | Pride
Esx-1 Mycobacterium tuberculosis 
ProteomicsThe E. coli type III secreted effectors NleB and EspL interact with the microtubule associated protein ensconsin to disrupt vesicle trafficking, part 1
Enteropathogenic and enterohaemorrhagic E. coli (EPEC and EHEC) translocate a set of type III effector proteins into host cells that are critical for bacterial virulence. These effectors subvert normal host pathways by interacting with a variety of targets within the cell, but the binding partners ...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2016-12-22 | PXD002933 | Pride
Human E. coli Effector Host-pathogen 
UnknownSpatial transcriptomics analysis of esophageal squamous precancerous lesions and their progression to esophageal cancer.
Not available
S-EPMC10409784 | biostudies-literature
UnknownA bacterial network of T3SS effectors counteracts host pro-inflammatory responses and cell death to promote infection.
Not available
S-EPMC12048508 | biostudies-literature
UnknownRecruitment of cyanobacteria by reverse transcription quantitative real-time PCR based on expression of Microcystis gene.
Not available
S-EPMC6599450 | biostudies-literature
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