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TranscriptomicsOvalbumin sensitized and challenged induces differential gene expression in mouse lungs
To gain insight into the promoting effect of ultrafine particle inhalation on development and progression of allergic asthma, we selected an experimental approach involving exposure to ultrafine carbon particles (UCP) and gene expression profiling of lungs from mice with experimental, ovalbumin indu...
ORGANISM(S): Mus musculus 
2010-06-10 | E-GEOD-6496 | biostudies-arrayexpress
TranscriptomicsUCP exposure of ovalbumin sensitized and challenged mice
To gain insight into the promoting effect of ultrafine particle inhalation on development and progression of allergic asthma, we selected an experimental approach involving exposure to ultrafine carbon particles (UCP) and gene expression profiling of lungs from mice with experimental, ovalbumin indu...
ORGANISM(S): Homo sapiens 
2010-06-10 | E-GEOD-6571 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C3H/HeJ and JF1/Msf strain mice to identify genetic risk factors for asthma and COPD
Comparison of lung function in C3H/HeJ and JF1/Msf strain mice to identify genetic risk factors for asthma and COPD.
ORGANISM(S): Mus musculus 
2007-03-08 | E-MEXP-855 | biostudies-arrayexpress
TranscriptomicsExpression profiling of lung tissue from 6-, 10- and 14-week-old Fra2 transgenic male mice
The transcription factor complex AP-1 (Activator protein 1) is composed of Jun (c-Jun, JunB, JunD) and Fos proteins (c-Fos, FosB, Fra-1, Fra-2) which control a variety of stress responses, including cell proliferation, apoptosis, inflammation, wound healing, and cancer. Individual Fos proteins have ...
ORGANISM(S): Mus musculus 
2011-12-01 | E-GEOD-23745 | biostudies-arrayexpress
MetabolomicsAutomated Label-free Quantification of Metabolites from Liquid Chromatography–Mass Spectrometry Data (Plasma)

Liquid chromatography coupled to mass spectrometry (LC-MS) has become a standard technology in metabolomics. In particular, label-free quantification based on LC-MS is easily amenable to large-scale studies and thus well suited to clinical metabolomics. Large-scale studies, however, require autom...

2015-12-16 | MTBLS234 | MetaboLights
TranscriptomicsRNA sequencing of tumor associated macrophages and T cells in clear cell renal cell carcinoma
Tumor associated macrophages and T cells were characterized in a cohort of 73 ccRCC and 5 healthy donors using mass cytometry. Macrophage and T cell subsets of interest were identified and sorted directly from samples known to contain a high frequency of these subsets. CD8+ PD-1- T cells (n=6), exha...
ORGANISM(S): Homo sapiens 
2017-05-04 | E-MTAB-5640 | biostudies-arrayexpress
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