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UnknownMolecular communication relays for dynamic cross-regulation of self-sorting fibrillar self-assemblies.
Not available
S-EPMC8612681 | biostudies-literature
TranscriptomicsGenome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting
So far, the annotation of translation initiation sites (TISs) has been based mostly upon bioinformatics rather than experimental evidence. We adapted ribosomal footprinting to puromycin-treated cells to generate a transcriptome-wide map of TISs in a human monocytic cell line. A neural network was tr...
ORGANISM(S): Homo sapiens 
2012-08-08 | E-GEOD-39561 | biostudies-arrayexpress
ProteomicsPost-column solvent addition enhances sensitivity of microflow-based bottom-up proteomics
We demonstrate that post-column addition of organic solvents leads to a strong enhancement of electrospray stability in microflow LC-MS experiments improving the sensitivity across the entire gradient, for early eluting peptides by up to tenfold. Post-column solvent addition did not negatively affec...
ORGANISM(S): Homo sapiens (Human) 
2019-05-28 | PXD011970 | Pride
Post-column solvent addition Hela digest Microflow lc-ms Bottom-up proteomics 
ProteomicsProteomic analysis of brain region and gender-specific synaptic protein expression in the adult mouse brain
In a wide range of synaptopathies a sex/gender bias in prevalence and clinical course has been reported. Therefore, analysis of the synaptic proteinaceous inventory in different brain regions in males and females is very desirable in understanding the molecular basis of brain function and the etiolo...
ORGANISM(S): Mus musculus (Mouse) 
2020-02-17 | PXD015610 | Pride
Sex/gender bias Prefrontal cortex Hippocampus Cerebellum Striatum Synaptic junction Label-free quantification Data-independent acquisition 
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