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TranscriptomicsDeep sequencing of endogenous mRNA from Caenorhabditis elegans in the presence and absence of 1-methylnicotinamide (MNA) and nicotinic acid (NA)
Sirtuins, a family of histone deacetylases, have a fiercely debated role in regulating lifespan of different species. Contrasting recent observations, we here find that overexpression of sir-2.1, the orthologue of mammalian SirT1, does extend C. elegans lifespan. Sirtuins are known to convert NAD+ i...
ORGANISM(S): Caenorhabditis elegans 
2013-08-09 | E-GEOD-49662 | biostudies-arrayexpress
MetabolomicsGC-MS based targeted metabolic profiling identifies changes in the wheat metabolome following deoxynivalenol treatment
Fusarium graminearum and related species commonly infest grains causing the devastating plant disease Fusarium head blight (FHB) and the formation of trichothecene mycotoxins. The most relevant toxin is deoxynivalenol (DON), which acts as a virulence factor of the pathogen. FHB is difficult to contr...
2014-10-17 | MTBLS112 | MetaboLights
UnknownDNA methylation profiling allows for characterization of atrial and ventricular cardiac tissues and hiPSC-CMs.
Not available
S-EPMC6560887 | biostudies-literature
TranscriptomicsExpression data of SW480 cells with TFAP2E overexpression and without TFAP2E (empty vector control)
AP2 transcription factors play important roles in development and cancer, we tried to clarify the role of the so far uncharacterised TFAP2E in colorectal cancer. We used GENE ST 1.0 Arrays to detail up and downregulated target genes of this AP-2 transcription factor. We used the ptarget mammalian ex...
ORGANISM(S): Homo sapiens 
2013-08-09 | E-GEOD-23698 | biostudies-arrayexpress
UnknownTherapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.
Not available
S-EPMC8362594 | biostudies-literature
UnknownAbdominal infections in the intensive care unit: characteristics, treatment and determinants of outcome.
Not available
S-EPMC4122779 | biostudies-literature
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