Sort   by:  
 Page size 
MetabolomicsFirst-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Diminished hepatocyte regeneration is a key feature of acute and chronic liver diseases and after extended liver resections, resulting in the inability to maintain or restore a sufficient functional liver mass. Therapies to restore hepatocyte regeneration are lacking, making liver transplantation...

2024-09-23 | MTBLS9434 | MetaboLights
ProteomicsMetabolic reconfiguration through SGLT2 inhibition improves metabolic waste excretion
Dapagliflozin is a member of a new class of medication called gliflozins indicated for the treatment of diabetes and has recently been also approved for the treatment of kidney and heart diseases. Gliflozins lower blood glucose levels by inhibition of the sodium glucose co-transporter 2 (SGLT2), whi...
ORGANISM(S): Mus musculus (Mouse) mouse gut metagenome 
2026-02-09 | PXD036817 | Pride
White adipose tissue Kidney Heart Skeletal muscle Lc-ms/ms Dapagliflozin Mouse Tmt Exploris 480 Murine Sglt2 inhibitors Liver Gut microbiome 
UnknownFailure to validate association between 12p13 variants and ischemic stroke.
Not available
S-EPMC2978046 | biostudies-literature
UnknownGenome-wide association analysis identifies 13 new risk loci for schizophrenia.
Not available
S-EPMC3827979 | biostudies-literature
UnknownA common variant mapping to CACNA1A is associated with susceptibility to exfoliation syndrome.
Not available
S-EPMC4605818 | biostudies-literature
UnknownVariability in working memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway.
Not available
S-EPMC4337973 | biostudies-literature
UnknownPopulation-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia.
Not available
S-EPMC8863274 | biostudies-literature
UnknownA polygenic resilience score moderates the genetic risk for schizophrenia.
Not available
S-EPMC7058518 | biostudies-literature
UnknownAnalysis of shared heritability in common disorders of the brain.
Not available
S-EPMC6097237 | biostudies-literature
UnknownGenomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.
Not available
S-EPMC6432650 | biostudies-literature
Sort   by:  
 Page size