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TranscriptomicsMaternal age effect on mouse oocytes: new biological insight from proteomic analysis
The long-standing view of 'immortal germ line versus mortal soma' poses a fundamental question in biology concerning how oocytes age in molecular terms. A mainstream hypothesis is that maternal aging of oocytes has its roots in gene transcription. Investigating the proteins resulting from mRNA trans...
ORGANISM(S): Mus musculus 
2014-04-15 | E-GEOD-42959 | biostudies-arrayexpress
TranscriptomicsHuman ART culture conditions prime mouse embryos for postimplantation development
With the increasing use of Assisted Reproductive Technologies (ART) for treatment of human infertility, there is an increasing requirement for embryo culture conditions that perform as similar to nature as possible. How good the match, however, cannot be tested experimentally in human. We solved th...
ORGANISM(S): Mus musculus 
2012-05-02 | E-GEOD-31414 | biostudies-arrayexpress
TranscriptomicsARTs versus developmental plasticity: blastocyst abnormalities after ICSI and embryo culture do not propagate into the offspring in mice
Following intracytoplasmic sperm injection (ICSI), in vitro culture (IVC) in ART media causes imbalance in the blastocyst's inner cell mass (ICM)with reduction of the primitive endoderm compartment compared to non-IVC blastocystsFollowing embryo transfer (ET), these imbalances do not influence birth...
ORGANISM(S): Mus musculus 
2016-08-25 | E-GEOD-50193 | biostudies-arrayexpress
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