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ProteomicsA bipartite motif of Mrx6 binds the Lon protease Pim1 N-terminal domain to confer substrates specificity and regulate mtDNA copy number
Mitochondrial DNA (mtDNA) copy number regulation remains in- completely understood, despite its critical importance in cellular function. In Saccharomyces cerevisiae, the protein Mrx6 is part of the Pet20-domain-containing protein family, which includes three members: Mrx6, Pet20, and Sue1. Notably,...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-01-22 | PXD061231 | Pride
Yeast Mitochondria Immunoprecipitation 
ProteomicsA bipartite motif of Mrx6 binds the Lon protease Pim1 N-terminal domain to confer substrates specificity and regulate mtDNA copy number
Mitochondrial DNA (mtDNA) copy number regulation remains in- completely understood, despite its critical importance in cellular function. In Saccharomyces cerevisiae, the protein Mrx6 is part of the Pet20-domain-containing protein family, which includes three members: Mrx6, Pet20, and Sue1. Notably,...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-11-18 | PXD061184 | Pride
Yeast Mitochondria Immunoprecipitation 
ProteomicsUracil phosphoribosyltransferase is required to establish a functional cytochrome b6/f complex
Arabidopsis uracil phosphoribosyltransferase (UPP) is an essential enzyme and plants lacking this enzyme are strongly compromised in chloroplast function. Our analysis of UPP amiRNA mutants has confirmed that this vital function is crucial to establish a fully functional photosynthesis as the RIESKE...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-12-09 | PXD052789 | Pride
Chloroplast Uracil phosphoribosyltransferase Arabidopsis High light Protease 
ProteomicsSurveying the chloroplast protein kinase preferences for cation cofactors in Arabidopsis thaliana
Survival of plants depends on their ability to adapt to ever-changing environmental conditions. Chloroplasts sense different stimuli and respond to ion fluxes in the cytosol triggering systemic responses under stress conditions. Indeed, changes in calcium and magnesium ion concentration in the chlor...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-03-11 | PXD037286 | Pride
Arabidopsis Chloroplast Maganese 
ProteomicsTargeted Translation Inhibition of Chloroplast and Mitochondrial mRNAs by Designer Pentatricopeptide Repeat Proteins
Pentatricopeptide repeat (PPR) proteins are crucial for organellar gene expression. To establish a tool for gene expression manipulation in Arabidopsis chloroplasts and genetically inaccessible mitochondria, we engineered designer (dPPR) proteins to specifically inhibit the translation of chloroplas...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-03-05 | PXD060146 | Pride
Arabidopsis Lc-msms 
ProteomicsShort chain fatty acids activate the glutamate-dependent acid resistance (Gad) system via the tRNA-modifying Mnm circuit in Escherichia coli
Acid resistance is an important trait of enterobacteria, enabling survival under extreme gastric acidity (pH < 2.5) and the moderate acidic conditions in the large intestine (pH 5 to 6). In Escherichia coli, the glutamate-dependent acid resistance (Gad) system – comprising the glutamate decarboxylas...
ORGANISM(S): Escherichia coli 
2026-09-14 | PXD076108 | Pride
Dia E. coli 
ProteomicsDelayed protein translocation protects mitochondria against toxic CAT-tailed proteins
In the ribosome-associated quality control acting on nuclear-encoded mitochondrial proteins (mitoRQC), Vms1 protects mitochondria from toxic effects of Rqc2-generated C-terminal alanyl and threonyl (CAT) tailed proteins that escaped proteosomal degradation facilitated by E3 ubiquitin ligase Ltn1. He...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-11-13 | PXD057575 | Pride
Yeast Quality control Mitochondria 
ProteomicsProteome analysis of TRANSLOCON OF THE OUTER CHLOROPLAST membrane 75 (TOC75) knockdown mutants
Artificial microRNA mutants of Toc75 were generated in Arabidopsis. Shotgun proteomics was with Col-0 and two independent knockdown lines.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-08-09 | PXD041299 | Pride
Arabidopsis thaliana Protein import Chloroplast 
ProteomicsOxygenic photosynthesis without photosystem I in a cyanobacterium
Cyanobacteria, algae and plants use oxygenic photosynthesis to fix CO2 and release O2. This process depends on ATP and NADPH, which are produced by the photosynthetic light reactions involving several multi-protein complexes and mobile electron carriers. These complexes include the two photosystems,...
ORGANISM(S): Synechocystis sp. PCC 6803 substr. GT-I 
2026-06-12 | PXD071953 | Pride
Photosynthesis Photosystem i Synechocystis 
ProteomicsEstablishment and application of a vesicle extraction method for clinical strains of Pseudomonas aeruginosa
Pseudomonas aeruginosa is a versatile pathogen capable of causing illnesses that range from mild infections to life-threatening conditions. Its virulence is driven by a wide array of factors, among which extracellular vesicles (EVs) have gained recognition as important contributors to its pathogenic...
ORGANISM(S): Pseudomonas aeruginosa 
2026-04-16 | PXD077187 | Pride
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