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TranscriptomicsGene expression profile in melanomas from Pdk1-inactivated BrafV600E::Pten-/- mice
Gene expression profiling was performed to access the changes in gene expression in melanomas from Pdk1-inactivated Brafv600E::Pten-/- mice. The expression profiles of the BrafV600E::Pten-/-::Pdk1-/- were compared to the BrafV600E::Pten-/-::Pdk+/+ genotypes. The analysis has identified several imp...
ORGANISM(S): Mus musculus 
2013-09-17 | E-GEOD-42187 | biostudies-arrayexpress
UnknownComparison Between Surgical Techniques for Correction of Congenital Syndactyly: A Systematic Review and Meta Analysis.
Not available
S-EPMC11559772 | biostudies-literature
UnknownUbiquitin Ligases Siah1a/2 Control Alveolar Macrophage Functions to Limit Carcinogen-Induced Lung Adenocarcinoma.
Not available
S-EPMC10330299 | biostudies-literature
UnknownUSP13 enzyme regulates Siah2 ligase stability and activity via noncatalytic ubiquitin-binding domains.
Not available
S-EPMC3149327 | biostudies-literature
UnknownGenetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma.
Not available
S-EPMC3955742 | biostudies-literature
UnknownAge-Associated Modulation of TREM1/2-Expressing Macrophages Promotes Melanoma Progression and Metastasis.
Not available
S-EPMC12352130 | biostudies-literature
ProteomicsAging in pancreatic ductal adenocarcinoma
Aging is a critical yet understudied determinant in pancreatic ductal adenocarcinoma (PDAC). Despite a strong epidemiological association with age, conventional PDAC preclinical models fail to capture the histopathological and stromal complexities that emerge in older organisms. Using an age-relevan...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-12 | PXD068597 | Pride
Pancreatic ductal adenocarcinoma Cancer-associated fibroblasts Aging Immunosuppression Metastasis 
UnknownThe Aging Microenvironment Is a Determinant of Immune Exclusion and Metastatic Fate in Pancreatic Cancer.
Not available
S-EPMC12768431 | biostudies-literature
UnknownFine tuning of the UPR by the ubiquitin ligases Siah1/2.
Not available
S-EPMC4014425 | biostudies-literature
UnknownThe E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion.
Not available
S-EPMC5752272 | biostudies-literature
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