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MetabolomicsChemotherapy Modulation by a Cancer-Associated Microbiota Metabolite (Targeted metabolomics - 2methylisocitrate)

Understanding how the microbiota produces regulatory metabolites is of significance for cancer and cancer therapy. Using a host-microbe-drug-nutrient 4-way screening approach, we evaluated the role of nutrition at the molecular level in the context of 5-fluorouracil toxicity. Notably, our screens...

2025-09-16 | MTBLS9994 | MetaboLights
MetabolomicsChemotherapy Modulation by a Cancer-Associated Microbiota Metabolite (Targeted metabolomics - fluoronucleotides)

Understanding how the microbiota produces regulatory metabolites is of significance for cancer and cancer therapy. Using a host-microbe-drug-nutrient 4-way screening approach, we evaluated the role of nutrition at the molecular level in the context of 5-fluorouracil toxicity. Notably, our screens...

2025-09-16 | MTBLS9991 | MetaboLights
Proteomics,MultiomicsIdentification SETD1A-binding proteins by Co-IP MS
The dataset contains the gelLC MS analysis of immunoprecipitated complex from full-lenght and truncated SETD1A. The protein was ectopically expressed and the binders immunoprecipitated in cell transduced with the empty vector were analyzed as control.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-08-01 | MSV000080012 | MassIVE
TranscriptomicsPlatform comparison and transcription profiling of mixed tissue RNA samples formulated to contain different ratios of RNA for each of four rat tissues (brain, liver, kidney, and testes) on Affymetrix RAE230A, CodeLink UniSet Rat I, and Agilent G4130A rat oligonucleotide arrays
This experiment is a test of a reagent that can provide a basis for performance assessments on Affymetrix RAE230A, CodeLink UniSet Rat I, and Agilent G4130A rat oligonucleotide arrays. The reagent is a set of two mixed tissue RNA samples formulated to contain different ratios of RNA for each of f...
ORGANISM(S): Rattus norvegicus 
2010-03-30 | E-TABM-16 | biostudies-arrayexpress
GenomicHIV-1 Host Genetics Among Injection Drug Users

The overarching goal of this project is to identify and characterize genetic determinants of HIV 1 susceptibility and resistance in samples of African American (AA) and European American (EA) injection drug users (IDUs) by conducting (1) a case/control genome-wide association (GWA) study of HIV 1...

phs000454 | dbGaP
ProteomicsA BioID-derived proximity interactome for SARS-CoV-2 proteins
The novel coronavirus SARS-CoV-2 is responsible for the ongoing COVID-19 pandemic and has caused a major health and economic burden worldwide. Understanding how SARS-CoV-2 viral proteins behave in host cells can reveal underlying mechanisms of pathogenesis and assist in development of antiviral ther...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-10-18 | MSV000088245 | MassIVE
UnknownAccumulation of oxidized LDL in the tendon tissues of C57BL/6 or apolipoprotein E knock-out mice that consume a high fat diet: potential impact on tendon health.
Not available
S-EPMC4264764 | biostudies-literature
TranscriptomicsA microfluidic platform enabling single cell RNA-seq of multigenerational lineages
We introduce a microfluidic platform that enables off-chip single-cell RNA-seq after multigenerationa lineage tracking under controlled culture conditions. Examination of lineage and cell cycle dependent transcriptional profiles in two cell types
ORGANISM(S): Mus musculus 
2015-12-22 | E-GEOD-74923 | biostudies-arrayexpress
ProteomicsImplantation-on-a-chip cellular proteome
We have designed an implantation-on-a-chip device to model the invasion of specialized fetal extravillous trophoblasts (EVTs) from an implanting embryo into the maternal decidua. We profiled the cellular proteome of sorted EVTs or endothelial cells from devices containing different cell compositions...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-01-12 | MSV000088677 | MassIVE
ProteomicsMarkers of neutrophil degranulation in the lung microenvironment linked to idiopathic pulmonary fibrosis severity and survival
Idiopathic pulmonary fibrosis (IPF) leads to progressive loss of lung function and mortality. Understanding mechanisms and markers of lung injury in IPF is paramount to improving outcomes for these patients. Despite the lack of systemic involvement in IPF, many analyses focus on identifying circulat...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-05-29 | MSV000098032 | MassIVE
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