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TranscriptomicsTranscription profiling of human cell lines freely cycling treated with 164 distinct small molecules - Broad Connectivity Map CMAP Set 1
A reference collection of genome-wide transcriptional expression data for bioactive small molecules. Experiment Overall Design: The current collection (build01) contains data for 164 distinct small molecules applied to freely cycling human cell lines, represented by 453 individual treatment and matc...
ORGANISM(S): Homo sapiens 
2008-12-06 | E-GEOD-5258 | biostudies-arrayexpress
ProteomicsThe proteome landscape of extracellular vesicles from prostate cancer cell lines
Proteome of extracellular vesicles (EVs) collected from prostate cancer cell lines - LNCaP, 22RV1, LNCaP 95, C4-2, DU145, PC3, NCI-H660, LASCPC-01, EF1.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-25 | MSV000096519 | MassIVE
TranscriptomicsDeciphering the molecular immune response to COVID-19 using single cell multi-omics
Multi-omics single-cell profiling of surface proteins, gene expression and lymphocyte immune receptors from hospitalised COVID-19 patient peripheral blood immune cells and healthy controls donors. Identification of the coordinated immune cell compositional and state changes in response to SARS-CoV-2...
ORGANISM(S): Homo sapiens 
2021-03-17 | E-MTAB-10026 | biostudies-arrayexpress
UnknownThe gain of function SCN1A disorder spectrum: novel epilepsy phenotypes and therapeutic implications.
Not available
S-EPMC9679167 | biostudies-literature
GenomicsGenomic Analysis of Pediatric Low Grade Gliomas

Pediatric low-grade gliomas (PLGGs) are among the most common solid tumors in children but, apart from mutations or duplications in the BRAF kinase in specific subclasses, few genetic driver events are known. Diffuse PLGGs compose a set of uncommon subtypes that exhibit invasive growth and are th...

phs000614.v1.p1 | EGA
ProteomicsMulti-omics analysis of plasma in atrial fibrillation patients
Comprehensive metabolomic and proteomic analyses reveal candidate biomarkers and related metabolic networks in atrial fibrillation.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-05-14 | MSV000083774 | MassIVE
UnknownDe Novo Mutations Affecting the Catalytic Cα Subunit of PP2A, PPP2CA, Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders.
Not available
S-EPMC6323609 | biostudies-literature
GenomicsWhole Genome Sequencing of a Triple Negative Breast Cancer Patient: Matched Primary Tumor, Normal, Metastasis and Xenograft samples

Breast Cancer Subject Participant ID 700064 (Source Sample names: 6888 and 206). We used massively parallel DNA sequencing technologies to screen entire genomes, in an unbiased manner, for genetic changes associated with tumor growth and metastasis. We describe the complete genome sequence ...

phs000245.v1.p1 | EGA
UnknownThe MOG antibody non-P42 epitope is predictive of a relapsing course in MOG antibody-associated disease.
Not available
S-EPMC11103329 | biostudies-literature
GenomicsInduction of sarcomas by mutant IDH2
More than 50% of patients with chondrosarcomas exhibit gain-of-function mutations in either isocitrate dehydrogenase 1 (IDH1) or IDH2. In this study, we performed genome-wide CpG methylation sequencing of chondrosarcoma biopsies and found that IDH mutations were associated with DNA hypermethylation ...
ORGANISM(S): Homo sapiens 
2013-10-21 | E-GEOD-50539 | biostudies-arrayexpress
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