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ProteomicsCombined assessment of global proteome, phosphoproteome and N-terminal protein cleavage to characterize altered platelet functions in human Scott syndrome
The Scott syndrome is a rare bleeding disorder associated with a mutation in the gene encoding anoctamin-6 (TMEM16F). After stimulation of Ca2+-mobilizing agonists, syndromatic platelets show a reduced phosphatidylserine exposure and do not form membrane blebs. Given the central role of anoctamin-6 ...
ORGANISM(S): Homo sapiens (Human) 
2016-08-24 | PXD002883 | Pride
Phosphoproteome Human platelets N-terminal chafradic Lc-ms Proteome 
TranscriptomicsGene expression profiling of metastatic lung cancer cell lines
During malignant disease progression, the extracellular matrix (ECM) of epithelial tumors accumulates inter-molecular cross-links between collagen strands; these cross-links enhance ECM stiffness and trigger tumor cell invasion and dissemination, but the mechanisms that regulate intra-tumoral collag...
ORGANISM(S): Mus musculus 
2015-03-12 | E-GEOD-49315 | biostudies-arrayexpress
UnknownOuabain-regulated phosphoproteome reveals molecular mechanisms for Na+, K+-ATPase control of cell adhesion, proliferation, and survival.
Not available
S-EPMC6704450 | biostudies-literature
TranscriptomicsTranscription profiling by array for comparison of industrial Escherichia coli strains on growth, transcriptome and proteome level in batch cultivations to identify strain specific features (subexperiment K-12 platform)
The objective of the current study was to evaluate the performance of frequently used E. coli K-12 strains HMS174 and RV308 in the context of industrial cultivations. To meet this objective, we carried out batch cultivations with high-glucose media in computer-controlled bioreactors and applied tran...
ORGANISM(S): Escherichia coli 
2013-08-19 | E-MARS-20 | biostudies-arrayexpress
UnknownGeochemical evidence for combustion of hydrocarbons during the K-T impact event.
Not available
S-EPMC2657452 | biostudies-literature
UnknownSorbitol-Based Glass Matrices Enable Dynamic Nuclear Polarization beyond 200 K.
Not available
S-EPMC11610384 | biostudies-literature
UnknownTesting for independence in J×K contingency tables with complex sample survey data.
Not available
S-EPMC4567525 | biostudies-literature
UnknownThe binding selectivity of vonoprazan (TAK-438) to the gastric H+, K+ -ATPase.
Not available
S-EPMC4626316 | biostudies-literature
UnknownZBTB11 Depletion Targets Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC.
Not available
S-EPMC11142081 | biostudies-literature
UnknownWilliam Jeffrey Scott
Not available
S-EPMC1126414 | biostudies-literature
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