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TranscriptomicsGlobal Transcriptional Analysis of Spontaneous Sakacin P-Resistant Mutant Strains of Listeria monocytogenes during Growth on Different Sugars
Subclass IIa bacteriocins have strong antilisterial activity and can control the growth of Listeria monocytogenes in food. However, L. monocytogenes may develop resistance towards such bacteriocins. In this follow-up study, the transcriptomes of a high level (L502-1) and a low level (L502-6) spontan...
ORGANISM(S): Listeria monocytogenes 
2011-04-15 | E-BUGS-110 | biostudies-arrayexpress
TranscriptomicsRole of a GntR-family response regulator LbrA in Listeria monocytogenes biofilm formation
The formation of Listeria monocytogenes biofilms contributes to persistent contamination in food processing facilities. A microarray comparison of L. monocytogenes between the transcriptome of the strong biofilm forming strain (Bfms) Scott A and the weak biofilm forming (Bfmw) strain F2365 was condu...
ORGANISM(S): Listeria monocytogenes 
2012-09-06 | E-GEOD-40598 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of metastatic lung cancer cell lines
During malignant disease progression, the extracellular matrix (ECM) of epithelial tumors accumulates inter-molecular cross-links between collagen strands; these cross-links enhance ECM stiffness and trigger tumor cell invasion and dissemination, but the mechanisms that regulate intra-tumoral collag...
ORGANISM(S): Mus musculus 
2015-03-12 | E-GEOD-49315 | biostudies-arrayexpress
TranscriptomicsPhysiology and genetic activity of Listeria monocytogenes during multi-hurdle stress induced cell death
The physiological basis of the hypothesis that temperature is the primary governing factor of bacterial cell inactivation under otherwise non-growth permissive conditions was investigated. Application of simultaneous low pH (pH 3.5) and low water activity (aw = 0.9; 2.5 M NaCl) conditions, applied t...
ORGANISM(S): Listeria monocytogenes 
2010-06-20 | E-GEOD-18796 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array for comparison of industrial Escherichia coli strains on growth, transcriptome and proteome level in batch cultivations to identify strain specific features (subexperiment K-12 platform)
The objective of the current study was to evaluate the performance of frequently used E. coli K-12 strains HMS174 and RV308 in the context of industrial cultivations. To meet this objective, we carried out batch cultivations with high-glucose media in computer-controlled bioreactors and applied tran...
ORGANISM(S): Escherichia coli 
2013-08-19 | E-MARS-20 | biostudies-arrayexpress
MetabolomicsDelayed gut microbiota maturation in the first year of life is a hallmark of pediatric allergic disease
Allergic diseases affect millions of people worldwide. An increase in their prevalence has been associated with alterations in the gut microbiome, i.e., the microorganisms and their genes within the gastrointestinal tract. Maturation of the infant immune system and gut microbiota occur in parallel; ...
2024-10-24 | MTBLS7919 | MetaboLights
TranscriptomicsGene expression profiles of murine granule neuron precursors and medulloblastoma
Sonic hedgehog (Shh) signals via Gli transcription factors to stimulate proliferation of granule neuron precursor cells (GNPs) in the cerebellum. Deregulation of Shh target genes often results in unrestrained GNP proliferation and eventually medulloblastoma (MB), the most common pediatric brain mali...
ORGANISM(S): Mus musculus 
2010-06-16 | E-GEOD-17702 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of in vivo-derived CMS4-met cells and the in vitro-derived CMS4.sel cells using CMS4 cells as a reference sample
The CMS4 sarcoma, kindly provided by A. DeLeo (University of Pittsburgh, Pittsburgh, PA), is a solid tumor of BALB/c (H-2d) origin, which grows aggressively in naive, syngeneic hosts following a s.c. transplant. Although the parental tumor cell line forms few metastatic foci in the lungs following i...
ORGANISM(S): Mus musculus 
2005-05-08 | E-MEXP-286 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of enforced HOXA1 expression in melanoma cell line (SkMel30)
We recently reported an oncogenomics-guided screening approach designed to identify genetic drivers of early stage melanoma metastasis, and in this study we functionally validate the top-scoring candidate, homeobox transcription factor A1 (HOXA1), by demonstrating HOXA1 robust effects on melanoma ce...
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-40422 | biostudies-arrayexpress
TranscriptomicsEstrogen-Related Receptor M-NM-3 (ERRM-NM-3) Regulates Oxygen-Dependent Expression of Voltage-gated Potassium (K+) Channels and Tissue Kallikrein during Human Trophoblast Differentiation
Estrogen-related receptor M-NM-3 (ERRM-NM-3) serves a critical O2-dependent regulatory role in differentiation of human cytotrophoblasts to syncytiotrophoblast. In this study, we investigated expression of genes encoding tissue kallikreins (KLK1) and voltage-gated K+ channels (KV7) during differenti...
ORGANISM(S): Homo sapiens 
2013-04-30 | E-GEOD-46463 | biostudies-arrayexpress
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