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TranscriptomicsSNP microarray based 24 chromosome aneuploidy screening is significantly more consistent than FISH
Many studies estimate that chromosomal mosaicism within the cleavage stage human embryo is high. However, comparison of two unique methods of aneuploidy screening of blastomeres within the same embryo has not been conducted and may indicate whether mosaicism is overestimated due to technical incons...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-20975 | biostudies-arrayexpress
UnknownNivolumab Monotherapy for First-Line Treatment of Advanced Non-Small-Cell Lung Cancer.
Not available
S-EPMC5569692 | biostudies-literature
UnknownNivolumab in Combination With Platinum-Based Doublet Chemotherapy for First-Line Treatment of Advanced Non-Small-Cell Lung Cancer.
Not available
S-EPMC5569693 | biostudies-literature
TranscriptomicsJuvenile obesity in Ossabaw swine produces artery-specific transcriptional changes
We adopted a transcriptome-wide microarray analysis approach to determine the extent to which vascular gene expression is altered as a result of juvenile obesity and identify obesity-responsive mRNAs. We examined transcriptional profiles in the left anterior descending coronary artery (LAD), perivas...
ORGANISM(S): Sus scrofa 
2013-05-29 | E-GEOD-41636 | biostudies-arrayexpress
TranscriptomicsSNP microarray based 24 chromosome aneuploidy screening demonstrates that cleavage stage FISH poorly predicts aneuploidy in embryos that develop to morphologically normal blastocysts
Preimplantation genetic diagnosis (PGD) of aneuploidy by fluorescence in situ hybridisation (FISH) has not delivered the expected clinical benefit. Many previous re-analysis studies of embryos deemed aneuploid by FISH on day 3 have found a high degree of chromosomal normalcy at the blastocyst stage...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-18932 | biostudies-arrayexpress
TranscriptomicsValidation of rapid embryo tracking using cell-free fetal DNA enriched from maternal circulation at 9 weeks gestation
Embryo DNA fingerprinting represents an important tool for tracking embryo-specific outcomes after multiple embryo transfer during IVF. The situation in which 2 embryos are transferred and only one implants represents a unique opportunity for the most well-controlled comparison of competent and inc...
ORGANISM(S): Homo sapiens 
2011-04-14 | E-GEOD-26404 | biostudies-arrayexpress
UnknownParental-reported allergic disorders and emergency department presentations for allergy in the first five years of life; a longitudinal birth cohort.
Not available
S-EPMC5964731 | biostudies-literature
TranscriptomicsSingle Cell Whole Genome Amplification Technique Impacts the Accuracy of SNP Microarray Based Genotyping and Copy Number Analyses
Methods of comprehensive microarray based analyses of single cell DNA are rapidly emerging. Whole genome amplification (WGA) remains a critical component for these methods to be successful. A number of commercially available WGA kits have been independently utilized in previous single cell microar...
ORGANISM(S): Homo sapiens 
2010-12-20 | E-GEOD-24690 | biostudies-arrayexpress
GenomicsWhole-Genome Sequencing of a Healthy Aging Cohort.
Studies of long-lived individuals have revealed few genetic mechanisms for protection against age-associated disease. Therefore, we pursued genome sequencing of a related phenotype-healthy aging-to understand the genetics of disease-free aging without medical intervention. In contrast with studies o...
EGAS00001002306 | EGA
UnknownAssociation of Exercise With Mortality in Adult Survivors of Childhood Cancer.
Not available
S-EPMC6181767 | biostudies-literature
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