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MetabolomicsComparative Metabolomic Sampling of Upper and Lower Airways by Four Different Methods to Identify Biochemicals That May Support Bacterial Growth
Bacteria need nutrients from the host environment to survive, yet we know little about which biochemicals are present in the airways (the metabolome), which of these biochemicals are essential for bacterial growth and how they change with airway disease. The aims of this pilot study were to develop ...
2019-06-13 | MTBLS179 | MetaboLights
TranscriptomicsDifferential Gene Expression between African American and European American Colorectal Cancer Patients
The incidence and mortality of colorectal cancer (CRC) is higher in African Americans (AAs) than in other ethnic groups in the U. S., but reasons for the disparities are unknown. We performed gene expression profiling and microsatellite instability (MSI) analysis of sporadic CRCs from AAs vs. Europe...
ORGANISM(S): Homo sapiens 
2012-05-22 | E-GEOD-28000 | biostudies-arrayexpress
UnknownMechanism of Rate Acceleration of Radical C-C Bond Formation Reaction by a Radical SAM GTP 3',8-Cyclase.
Not available
S-EPMC7256450 | biostudies-literature
UnknownRevisiting One-Carbon Metabolites in Human Breast Milk: Focus on S-Adenosylmethionine.
Not available
S-EPMC9863976 | biostudies-literature
ProteomicsProteotranscriptomic profiling of 231-BR breast cancer cells
These files accompany a submission to Mol Cell Proteomics: 'Proteotranscriptomic profiling of 231-BR breast cancer cells: Identification of potential biomarkers and therapeutic targets for brain metastasis' Authors: Matthew D. Dun, Robert J. Chalkley, Sam Faulkner, Sheridan Keene, Kelly Avery-Kiejda...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2014-10-29 | MSV000078911 | MassIVE
TranscriptomicsGene expression profiles of murine granule neuron precursors and medulloblastoma
Sonic hedgehog (Shh) signals via Gli transcription factors to stimulate proliferation of granule neuron precursor cells (GNPs) in the cerebellum. Deregulation of Shh target genes often results in unrestrained GNP proliferation and eventually medulloblastoma (MB), the most common pediatric brain mali...
ORGANISM(S): Mus musculus 
2010-06-16 | E-GEOD-17702 | biostudies-arrayexpress
TranscriptomicsStructural and functional characterization of the N-terminus of Schizosaccharomyces pombe Cwf10
The spliceosome is a dynamic macromolecular machine that catalyzes the removal of introns from pre-mRNA to make mature message. Schizosaccharomyces pombe Cwf10 (homolog Saccharomyces cerevisiae Snu114 and of Human U5-116K), an integral member of the U5 snRNP, is a GTPase that shares sequence homolog...
ORGANISM(S): Schizosaccharomyces pombe 
2013-09-25 | E-GEOD-47573 | biostudies-arrayexpress
TranscriptomicsRole of a GntR-family response regulator LbrA in Listeria monocytogenes biofilm formation
The formation of Listeria monocytogenes biofilms contributes to persistent contamination in food processing facilities. A microarray comparison of L. monocytogenes between the transcriptome of the strong biofilm forming strain (Bfms) Scott A and the weak biofilm forming (Bfmw) strain F2365 was condu...
ORGANISM(S): Listeria monocytogenes 
2012-09-06 | E-GEOD-40598 | biostudies-arrayexpress
GenomicsSpo11-oligo mapping in bas1 and ino4 mutants
Meiotic recombination is initiated by developmentally programmed DNA double-strand breaks (DSBs). In S. cerevisiae, the vast majority of DSBs occur in the nucleosome-depleted regions at gene promoters, where transcription factors (TFs) bind. It has been proposed that TF binding can stimulate DSB for...
ORGANISM(S): Saccharomyces cerevisiae 
2015-08-21 | E-GEOD-67910 | biostudies-arrayexpress
TranscriptomicsRNA-seq reveals differential gene expression in Staphylococcus aureus at single-nucleotide resolution
Staphylococcus aureus is a gram-positive cocci and an important human commensal bacteria and pathogen. S. aureus infections are increasingly difficult to treat because of the emergence of highly resistant MRSA (Methicillin-resistant S. aureus) strains. Here we present a method to study differential...
ORGANISM(S): Staphylococcus aureus 
2013-11-07 | E-GEOD-48896 | biostudies-arrayexpress
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