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MetabolomicsIonomic, Metabolomic, and Enzymatic Responses of the Sea Cucumber Apostichopus japonicus to Single and Combined Salinity and Metal Stress

Desalination brine discharge poses emerging threats to benthic marine organisms through combined salinity stress and metal contamination. This study investigated the individual and combined effects of salinity (35 ppt) and metal exposure (Cu, Fe, and Cd) on the sea cucumber Apostichopus japonicus...

2026-03-18 | MTBLS14079 | MetaboLights
ProteomicsiTRAQ - based proteomic analyses of sea cucumber Apostichopus japonicus in response to the stresses of heat, hypoxia and heat plus hypoxia
The proteomic profile of sea cucumber was conducted to identify key proteins involved in stress resistance based on the iTRAQ technique, including heat, hypoxia and heat plus hypoxia stress.
ORGANISM(S): Stichopus japonicus (Sea cucumber) 
2019-01-07 | PXD008472 | Pride
Hypoxia stress Proteomic analysis Sea cucumber Itraq Heat stress 
TranscriptomicsGene expression profile of regenerating intestine in the sea cucumber H. glaberrima
Regenerating intestine tissues were compared with normal (non-regenerating tissues) to determine the gene expression profile at early stages of regeneration (3, 7 and 14 days post- evisceration (dpe)). Immuno activated tissues with LPS were compared with Normal (non-regenerating tissues) and regen...
ORGANISM(S): Holothuria glaberrima 
2010-05-18 | E-GEOD-16182 | biostudies-arrayexpress
TranscriptomicsHigh-throughput sequencing reveals differential expression of miRNAs in intestine from sea cucumber during aestivation [miRNA-Seq]
The regulatory role of miRNA in gene expression is an emerging hot new topic in the control of hypometabolism. Sea cucumber aestivation is a complicated physiological process that includes obvious hypometabolism as evidenced by a decrease in the rates of oxygen consumption and ammonia nitrogen excre...
ORGANISM(S): Apostichopus japonicus 
2014-06-06 | E-GEOD-48867 | biostudies-arrayexpress
TranscriptomicsLarge-scale identification and comparative analysis of miRNA expression profile in the respiratory tree of the sea cucumber Apostichopus japonicus during aestivation (part 2)
The sea cucumber Apostichopus japonicus withstands high water temperatures in the summer by suppressing metabolic rate and entering a state of aestivation. We hypothesized that changes in the expression of miRNAs could provide important post-transcriptional regulation of gene expression during hypom...
ORGANISM(S): Apostichopus japonicus 
2014-10-01 | E-GEOD-52225 | biostudies-arrayexpress
Genomicssea cucumber metagenome
sea cucumber metagenome Raw sequence reads
PRJNA818100 | ENA
ProteomicsLysine acetylproteome profiling reveals key acetylated proteins involved in heat shock response in the sea cucumber Apostichopus japonicus
Intestine of a total of 9 idividuals was sampled. The individuals were collected from 3 groups: Control (C), Heat stress 6h (HS6h) and Heat stress 48h (HS48h).After protein extraction,trypsin digestion and enrichment of Lys-acetylated peptides, the eluted peptides was applied with LC-MS/MS detection...
ORGANISM(S): Stichopus japonicus (Sea cucumber) 
2019-11-12 | PXD013929 | Pride
Intestine Heat stress Apostichopus japonicus Acetylproteome 
ProteomicsComparative phosphoproteomic and acetylated proteomic analysis of intestine regeneration in the sea cucumber Apostichopus japonicus
Sea cucumbers have a striking capacity to regeneratemost of their viscera after evisceration, which has drawn theinterest ofmany researchers. In this study, we perform quantitative phosphoproteomics proteomic to analyze the proteinphosphorylation and acetylation changes between regenerative intestin...
ORGANISM(S): Stichopus japonicus (Sea cucumber) 
2018-10-22 | PXD008374 | Pride
Regeneration Sea cucumber Phosphoproteomic Acetylated proteomic Protein modified regulation 
TranscriptomicsNA-Seq reveals dynamic changes of gene expression in key stages of intestine regeneration in the sea cucumber Apostichopus japonicus.
Sea cucumbers (Holothuroidea; Echinodermata) have the capacity to regenerate lost tissues and organs.We used RNA-Seq to determine gene expression profiles associated with intestinal regeneration in A. japonicus at 3, 7, 14 and 21 days post evisceration (dpe) At least 15 individuals per stage, at 3,...
ORGANISM(S): Apostichopus japonicus 
2015-01-01 | E-GEOD-44995 | biostudies-arrayexpress
Genomicssea cucumber metagenome
sea cucumber pioneer microbiome
PRJDB12340 | ENA
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