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Mycobacterium tuberculosis variant pinnipedii strain:sea lion | isolate:sea lion Genome sequencing and assembly
In this study we assessed the utility of a microarray to identify changes in gene expression predictive of health status by interrogating blood samples from California sea lions in rehabilitation. 73 California sea lion blood samples. 28 Females and 45 males. Animals were divided into 4 groups based...
ORGANISM(S): Zalophus californianus 
Domoic acid toxicosis (DAT) in California sea lions (Zalophus californianus) is caused by exposure to the marine biotoxin domoic acid and has been linked to massive stranding events and mortality. Diagnosis is based on clinical signs in addition to the presence of domoic acid in body fluids. Chronic...
ORGANISM(S): Zalophus californianus (California sealion) 
2015-04-30 | PXD001606 | Pride
We conducted a pilot label-free LC-MS/MS study to profile and compare the cerebral spinal fluid from California sea lions with domoic acid toxicosis and without domoic acid toxicosis. CSF samples from a 8 animals with DAT and 3 controls were run on a nano LC-MS/MS (Triple TOF) and searched against a...
ORGANISM(S): Zalophus californianus (California sealion) 
2015-09-21 | PXD002105 | Pride
This data is a re-analysis of samples used in a prior study (doi:10.1371/journal.pone.0123295) evaluating plasma candidate biomarkers of chronic domoic acid toxicosis (DAT) in California sea lions (Zalophus californianus). The previous study used 2D-gel electrophoresis to analyze plasma from a train...
ORGANISM(S): Zalophus californianus (California sealion) 
2020-07-17 | PXD020366 | Pride
The neurotoxic amino acid, domoic acid, is naturally produced by marine phytoplankton and presents a significant health threat to marine mammal and human populations. Currently, diagnostic tools to assess exposure are not available, yet concerns regarding health impacts associated with low-level re...
ORGANISM(S): Danio rerio 
Since 1998, California sea lion stranding events associated with domoic acid toxicosis (DAT) have consistently increased and there are no practical non-lethal clinical tests for the diagnosis of domoic acid toxicosis that can be utilized in a large-scale rehabilitation facility. Proteomic analysis w...
ORGANISM(S): Zalophus californianus (California sealion) 
2023-04-05 | PXD041356 | Pride
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