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ProteomicsA novel translocon for biogenesis of multi-pass membrane proteins
A novel 370 kDa translocon comprising Sec61 and five accessory factors acting co-translationally with ribosomes to fold and insert multi-pass membrane proteins was identified, purified and analyzed structurally by single particle cryo-EM and cross-linking mass spectrometry. The purified ribosome-tr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-07-08 | MSV000084065 | MassIVE
UnknownCharacterization of Sec-translocon-dependent extracytoplasmic proteins of Rickettsia typhi.
Not available
S-EPMC2546805 | biostudies-literature
UnknownSEC-Translocon Dependent Extracytoplasmic Proteins of Candidatus Liberibacter asiaticus.
Not available
S-EPMC5167687 | biostudies-literature
UnknownIn vitro membrane protein synthesis inside Sec translocon-reconstituted cell-sized liposomes.
Not available
S-EPMC5093552 | biostudies-literature
UnknownForces on Nascent Polypeptides during Membrane Insertion and Translocation via the Sec Translocon.
Not available
S-EPMC6303271 | biostudies-literature
UnknownDynamics of Co-translational Membrane Protein Integration and Translocation via the Sec Translocon.
Not available
S-EPMC7338273 | biostudies-literature
UnknownPartially inserted nascent chain unzips the lateral gate of the Sec translocon.
Not available
S-EPMC6776908 | biostudies-literature
ProteomicsA peptidisc-based AP/MS approach to explore the interactome of the bacterial Sec translocon
We recently presented the peptidisc membrane mimetic for the global reconstitution of membrane proteomes into water-soluble detergent-free particles, termed peptidisc library. We here develop a method that combines the peptidisc library with affinity pulldown and mass spectrometry (AP/MS) to explore...
ORGANISM(S): Escherichia coli (strain K12 / W3110 / ATCC 27325 / DSM 5911) 
2023-03-22 | PXD018866 | Pride
Mass spectrometry Affinity tagging Sec translocon Protein translocation Peptidisc Protein complex analysis Membrane mimetics Membrane protein complexes Protein-protein interactions Affinity purification/mass spectrometry (ap/ms) 
UnknownStructure of the Inhibited State of the Sec Translocon.
Not available
S-EPMC7427319 | biostudies-literature
UnknownArchitecture of the active post-translational Sec translocon.
Not available
S-EPMC7849165 | biostudies-literature
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