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ProteomicsIdentification of SEC61B as a novel regulator of calcium flux and platelet hyperactivity in diabetes mellitus
Platelet hyperactivity contributes to increased cardiovascular thrombosis in diabetes. Intracellular and released proteins control platelet activity however there are limited proteomic studies of the diabetic platelet. We isolated platelets from 34 patients without, and 42 patients with type 2 diabe...
ORGANISM(S): Homo sapiens (Human) 
2025-04-19 | PXD049321 | Pride
Sec61b Calcium Er stress Diabetes Translocon Platelet 
UnknownSEC61B regulates calcium flux and platelet hyperreactivity in diabetes.
Not available
S-EPMC12352904 | biostudies-literature
ProteomicsSec61b-interacting proteins under ER stress conditions
Sec61b-interacting proteins under ER stress conditions from HEK293 cells
ORGANISM(S): Homo Sapiens (human) 
2025-12-15 | PXD054523 | JPOST Repository
ProteomicsRTN3 and control IP mass spectrometry
Immunoprecipitation of RTN3, Sec61B, and RTN4. Sec61B and RTN4 serve as controls.
ORGANISM(S): Homo sapiens (Human) 
2021-08-16 | PXD024725 | Pride
Er-phagy Rtn3 
UnknownmRNA encoding Sec61β, a tail-anchored protein, is localized on the endoplasmic reticulum.
Not available
S-EPMC4582399 | biostudies-literature
ProteomicsGenetically encoded photocatalytic protein labeling enables spatially-resolved profiling of intracellular proteome
Mapping the subcellular organization of proteins is crucial for understanding their biological functions. Herein, we report a reactive oxygen species induced protein labeling and identification (RinID) method for profiling subcellular proteome in the context of living cells. Our method capitalizes o...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD037678 | Pride
Minisog sopp3 proximity labeling photosensitive protein singlet oxygen 
UnknownProteomic analysis of solid pseudopapillary tumor of the pancreas reveals dysfunction of the endoplasmic reticulum protein processing pathway.
Not available
S-EPMC4188989 | biostudies-literature
UnknownMolecular Mechanisms of Isolated Polycystic Liver Diseases.
Not available
S-EPMC9104337 | biostudies-literature
ProteomicsProteomic analysis of human lung cancer and paracancer tissues
The treatment of LUAD mainly includes surgery, radiotherapy and chemotherapy. However, the clinical population of LUAD chemotherapy drugs is limited, and patients inevitably have the problem of drug resistance. The development of LUAD therapeutic drugs can provide more treatment strategies for patie...
ORGANISM(S): Homo Sapiens 
PXD062672 |
UnknownDynamic tracking and identification of tissue-specific secretory proteins in the circulation of live mice.
Not available
S-EPMC8410947 | biostudies-literature
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