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TranscriptomicsGene expression profiling in porcine chronic myocardial ischemia treated with intramyocardial injections of secretome
Closed-chest reperfused MI was induced in pigs by 90-min occlusion, followed by reperfusion of the mid LAD (day 0) and by cardiac MRI with late enhancement (LE) at day 3. At day 30 the animals received either porcine APOSEC (n=8) or placebo medium (n=8) in a randomized manner, injected into the bord...
ORGANISM(S): Sus scrofa 
2013-12-31 | E-GEOD-47397 | biostudies-arrayexpress
TranscriptomicsAnnotating the secretome of mature primary human muscle cells
The Skeletal muscle is a metabolic active tissue that secretes various proteins. These so called myokines act auto-, para- and endocrine affecting muscle physiology and exert systemic effects on other tissues and organs. Myokines are also described to play a crucial role in the pathophysiology of me...
ORGANISM(S): Homo sapiens 
2013-12-03 | E-GEOD-45473 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human colorectal cancer cell line COLO320DM treated with the secretome of irradiated or control cancer-associated fibroblasts for 6 or 48 hours
Cancer-associated fibroblasts (CAFs) are an important component of the desmoplastic stroma in rectal cancer. Preoperative chemoradiotherapy plays a pivotal role in the management of locally advanced rectal cancer. Patient-derived CAFs were used to evaluate the response to radiotherapy and its conseq...
ORGANISM(S): Homo sapiens 
2017-11-01 | E-MTAB-5364 | biostudies-arrayexpress
ProteomicsScreening of Adipose mesenchymal stem cell derived secretome
The objective of this project is secreening the constituent of adipose derived mesenchymal stem cell secretome.
ORGANISM(S): Homo Sapiens 
PXD045254 |
ProteomicsHigh Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells
Enteroendocrine cells (EECs) sense intestinal content and release hormones to regulate gastrointestinal activity and systemic metabolism and food intake. Little is known about the molecular make-up of human EEC subtypes and the regulated secretion of individual hormones. Here we describe an organoid...
ORGANISM(S): Homo sapiens (Human) 
2020-05-15 | PXD017468 | Pride
Organoids Peptide hormones Eec Secretome 
GenomicsSecretome translation shaped by Lysosomes and Lunapark-marked ER Junctions
Secretome translation shaped by Lysosomes and Lunapark-marked ER Junctions
PRJNA1334604 | ENA
TranscriptomicsGene expression profiling and secretome analysis differentiate Adult-Derived Human Liver Stem/progenitor Cells and human hepatic stellate cells
Adult-derived human liver stem/progenitor cells (ADHLSC) are obtained after primary culture of the liver parenchymal fraction. The cells are of fibroblastic morphology and exhibit a hepato-mesenchymal phenotype. Hepatic stellate cells (HSC) derived from the liver non-parenchymal fraction present a c...
ORGANISM(S): Homo sapiens 
2015-05-11 | E-GEOD-49995 | biostudies-arrayexpress
TranscriptomicsSecretome translation shaped by Lysosomes and Lunapark-marked ER Junctions
This study investigates how translation of mRNAs encoding membrane and secretory proteins (“secretome mRNAs”) is spatially regulated in human cells. Using live-cell imaging, proteomics, and RNA-sequencing, we show that Lunapark (LNPK)–enriched ER junctions and lysosomes form specialized hubs that en...
ORGANISM(S): Homo sapiens 
2025-09-30 | GSE309254 | GEO
TranscriptomicsDECIDUALIZATION INDUCES A SECRETOME SWITCH IN THE PERIVASCULAR NICHE CELLS OF THE HUMAN ENDOMETRIUM
The endometrial perivascular microenvironment is rich in mesenchymal stem-like cells that express type 1 integral membrane protein Sushi domain containing 2 (SUSD2) but the role of these cells in the decidual transformation of this tissue in pregnancy is unknown. We used an antibody directed against...
ORGANISM(S): Homo sapiens 
2014-10-29 | E-GEOD-57182 | biostudies-arrayexpress
UnknownSecretome translation shaped by lysosomes and lunapark-marked ER junctions.
Not available
S-EPMC12727531 | biostudies-literature
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