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ProteomicsStructural dynamics and immunogenicity of the recombinant and outer membrane vesicle-embedded Meningococcal antigen NadA
The structure and conformation adopted by protein vaccine antigens significantly influence the exposure of their antigenic determinants. Structural knowledge of antigens in native state could drive the design of recombinant vaccines that resemble their cognate native forms, although such information...
ORGANISM(S): Escherichia coli 
2025-09-15 | PXD058197 | Pride
Nada Hdx-ms 
TranscriptomicsTimEX from human embryonic stem cells, mesenchymal stem cells, and erythroid cells
The organization of mammalian DNA replication is poorly understood. We have produced genome-wide high-resolution dynamic maps of the timing of replication in human erythroid, mesenchymal and embryonic stem cells using TimEX, a method that relies on gaussian convolution of massive, highly redundant d...
ORGANISM(S): Homo sapiens 
2009-11-04 | E-GEOD-18679 | biostudies-arrayexpress
ProteomicsProteomic analysis of several non pathogenic mutants from Botrytis cinerea.
The grey mould fungus Botrytis cinerea is a typical necrotrophic fungus that can infect hundreds of host plants, including high-value crops such as grapevine, strawberry and tomato. In order to find new important genes involved in the fungal virulence, a mutant library was generated by random insert...
ORGANISM(S): Botryotinia fuckeliana (Noble rot fungus) (Botrytis cinerea) 
2021-11-03 | PXD013359 | Pride
Botrytis cinerea Quantitative proteome Non phytopathogenic mutant 
TranscriptomicsTranscription profiling by array of human dendritic cells after Poly(I:C)-based or PGE2-based maturation
Generation of human monocyte-derived DCs Peripheral blood mononuclear cells (PBMC) were isolated by Ficoll density centrifugation from buffy coats or whole blood of healthy donors and resuspended in serum-free medium (CellGro, CellGenix GmbH, Freiburg, Germany), supplemented with penicillin (50U/ml)...
ORGANISM(S): Homo sapiens 
2008-11-01 | E-MEXP-1230 | biostudies-arrayexpress
MetabolomicsA metabolomics approach to unravel the regulating role of phytohormones towards carotenoid metabolism in tomato fruit. (Lutein Metabolism)
Carotenoids are important secondary metabolites, which have been recognized as an essential component of the human diet because of their valuable beneficial health effects. With this rationale, there is a continuous aim to define the distribution of these compounds in plants, to better understand th...
2014-08-31 | MTBLS108 | MetaboLights
MetabolomicsA metabolomics approach to unravel the regulating role of phytohormones towards carotenoid metabolism in tomato fruit. (Lycopene metabolism)
Carotenoids are important secondary metabolites, which have been recognized as an essential component of the human diet because of their valuable beneficial health effects. With this rationale, there is a continuous aim to define the distribution of these compounds in plants, to better understand th...
2014-08-31 | MTBLS111 | MetaboLights
MetabolomicsA metabolomics approach to unravel the regulating role of phytohormones towards carotenoid metabolism in tomato fruit. (Zeaxanthin metabolism)
Carotenoids are important secondary metabolites, which have been recognized as an essential component of the human diet because of their valuable beneficial health effects. With this rationale, there is a continuous aim to define the distribution of these compounds in plants, to better understand th...
2014-08-31 | MTBLS107 | MetaboLights
MetabolomicsA metabolomics approach to unravel the regulating role of phytohormones towards carotenoid metabolism in tomato fruit. (alpha-carotene metabolism)
Carotenoids are important secondary metabolites, which have been recognized as an essential component of the human diet because of their valuable beneficial health effects. With this rationale, there is a continuous aim to define the distribution of these compounds in plants, to better understand th...
2014-08-31 | MTBLS109 | MetaboLights
MetabolomicsA metabolomics approach to unravel the regulating role of phytohormones towards carotenoid metabolism in tomato fruit. (beta-carotene)
Carotenoids are important secondary metabolites, which have been recognized as an essential component of the human diet because of their valuable beneficial health effects. With this rationale, there is a continuous aim to define the distribution of these compounds in plants, to better understand th...
2014-08-31 | MTBLS110 | MetaboLights
TranscriptomicsStressor mRNA expression profiling of three different stressors in the water flea Daphnia magna
Microarray analyses were used to evaluate patterns of gene transcription following exposure of the waterflea Daphnia magna to two natural and one anthropogenic stressor. cDNA microarrays compiled of three life stage specific and three stressor-specific EST libraries, yielding 1734 different EST sequ...
ORGANISM(S): Daphnia magna 
2013-09-01 | E-GEOD-24322 | biostudies-arrayexpress
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