Sort   by:  
 Page size 
ProteomicsImproved plasma membrane proteome coverage with a label-free non-affinity-purified workflow
The proteins of the cellular plasma membrane perform important functions relating to homeostasis and intercellular communication. Due to its overall low cellular abundance, amphipathic character, and low membrane-to-cytoplasm ratio, the plasma membrane proteome has been challenging to isolate and ch...
ORGANISM(S): Homo sapiens (Human) 
2017-01-31 | PXD004801 | Pride
Label-free  proteomics  plasma membrane  go term  leukemia 
ProteomicsMus musculus primary CD4+ T cell di-glycine remnant and whole cell proteomics
It is known that ubiquitination is important for T cell receptor (TCR) signaling during T cell activation but the breadth of ubiquitination events triggered during TCR signaling is not completely understood. This dataset utilizes di-glycine remnant profiling combined with mass spectrometry to identi...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-09 | PXD012831 | Pride
Mus musculus primary cd4+ t cell di-glycine remnant and whole cell proteomics 
ProteomicsComparative evaluation of different sample preparation workflows for reproducible, quantitative, and in-depth analysis of urine proteomics
The growing field of urinary proteomics has provided a promising opportunity to identify biomarkers useful for diagnosis and prognostication of a number of diseases. Urine is abundant and readily collected in a non-invasive manner which makes it eminently available for testing, however sample prepar...
ORGANISM(S): Homo sapiens (Human) 
2020-03-06 | PXD016273 | Pride
Reproducibility Urine proteomics Mass spectrometry Preomics ist Mstren Sample preparation Label-free S-trap 
ProteomicsCul4b promotes CD4 T cell expansion by aiding the repair of damaged DNA
The capacity for T cells to become activated and clonally expand during pathogen invasion is pivotal for protective immunity. Our understanding of how T cell receptor (TCR) signaling prepares cells for this rapid expansion remains limited. We have identified an E3 ubiquitin ligase, Cul4b, that regul...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-04 | PXD017699 | Pride
Dcaf1 Crl4 E3 ubiquitin ligase T cell receptor Apoptosis Smc1a Cul4b Cell cycle T cells Proliferation Adaptive immune response Dna damage response 
ProteomicsItch attenuates CD4 T cell proliferation in mice by limiting WBP2 protein stability
To mount an anti-pathogen response, CD4 T cells must undergo rapid cell proliferation. However, poorly controlled expansion can result in diseases such as autoimmunity. One important regulator of T cell activity is the E3 ubiquitin ligase Itch. Itch deficient patients suffer from extensive autoinfla...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-07 | PXD019272 | Pride
Proliferation E3 ubiquitin ligase Cell cycle Autoinflammation 
ProteomicsHs_PFrontalCortex_Silac
Human postmortem frontal cortex proteome
ORGANISM(S): Homo Sapiens (human) 
2012-12-31 | PAe005153 | PeptideAtlas
Sort   by:  
 Page size