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TranscriptomicsGDF5 variant with superior healing capacity
Seventy-two female Sprague-Dawley rats underwent a 5 mm critical-sized femoral segmental defect followed by stabilization with a custom-made unilateral external fixator. Following femoral defect generation, absorbable type I bovine collagen sponges were loaded either with 50 ug GDF5wt or 50 ug GDF5N...
ORGANISM(S): Rattus norvegicus 
2015-01-15 | E-MTAB-2249 | biostudies-arrayexpress
TranscriptomicsTranscriptomic landscape of lncRNAs in Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a complex multi-factorial inflammatory disease with Crohn’s disease (CD) and ulcerative colitis (UC) being the two most common forms. A number of transcriptional profiling studies have provided compelling evidence that describe the role of protein-coding genes and...
ORGANISM(S): Homo sapiens 
2015-04-10 | E-GEOD-67106 | biostudies-arrayexpress
GenomicsDistinct Global Shifts in Genomic Binding Profiles of Limb Malformation Associated HOXD13 Mutations
We applied ChIP-seq to explore the effect of missense mutations in TFs on their genome wide binding profile. Using a retroviral expression system in chicken mesenchymal stem cells, we elucidated the mechanism underlying a novel missense mutation in HOXD13 (Q317K) associated with a complex hand and f...
ORGANISM(S): Gallus gallus 
2013-08-19 | E-GEOD-44799 | biostudies-arrayexpress
UnknownBlood culture practices and microbiological capacity for sepsis diagnostics in Europe (2021-2022): a cross-sectional analysis of the European Sepsis Care Survey.
Not available
S-EPMC12771334 | biostudies-literature
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