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TranscriptomicsSorting of Drosophila small silencing RNAs partitions microRNA* strands into the RNA interference pathway
In flies, small silencing RNAs are sorted between Argonaute1 (Ago1), the central protein component of the microRNA (miRNA) pathway, and Argonaute2 (Ago2), which mediates RNA interference. Extensive double-stranded characterM-bM-^@M-^Tas is found in small interfering RNAs (siRNAs)M-bM-^@M-^Tdirects d...
ORGANISM(S): Drosophila melanogaster 
2009-10-31 | E-GEOD-18806 | biostudies-arrayexpress
TranscriptomicsEndogenous siRNAs derived from transposons and mRNAs in Drosophila somatic cells
Small interfering RNAs (siRNAs) direct RNA interference (RNAi) in eukaryotes. In flies, somatic cells produce siRNAs from exogenous double-stranded RNA as a defense against viral infection. Here, we identify 21-nt long, endogenous siRNAs (endo-siRNAs) corresponding to transposons and heterochromatic...
ORGANISM(S): Drosophila melanogaster 
2008-04-10 | E-GEOD-11019 | biostudies-arrayexpress
UnknownA 5'-uridine amplifies miRNA/miRNA* asymmetry in Drosophila by promoting RNA-induced silencing complex formation.
Not available
S-EPMC3127740 | biostudies-literature
ProteomicsImiquimod in human CD8+ T cells
Blood CD8 T cells from six healthy blood donors were treated with the TLR7 agonist imiquimod + IL-2 in T cell enriched medium overnight in vitro (the controls were incubated with T cell enriched medium + IL-2 only). After approx. 21 h the in solution digest protocol was started.
ORGANISM(S): Homo sapiens (Human) 
2024-04-29 | PXD038621 | Pride
Imiquimod Cd8 t cells 
UnknownTiming of developmentally programmed excision and circularization of Paramecium internal eliminated sequences.
Not available
S-EPMC85339 | biostudies-literature
TranscriptomicsHistone acetylation and DNA demethylation of T-cells result in an anaplastic large cell lymphoma-like phenotype.
A characteristic feature of anaplastic large cell lymphoma (ALCL) is the significant reduction of the T-cell expression program despite its T-cell origin, a finding very similar to the loss of B-cell identity of classical Hodgkin lymphoma (cHL). Previously we demonstrated that epigenetic mechanisms ...
ORGANISM(S): Homo sapiens 
2012-08-19 | E-GEOD-26101 | biostudies-arrayexpress
TranscriptomicsRERG is a novel ras-related, estrogen-regulated and growth-inhibitory gene in breast cancer
Using microarray analysis, we identified a unique ras superfamily gene, termed RERG (ras-related and estrogen-regulated growth inhibitor), whose expression was decreased or lost in a significant percentage of primary human breast tumors that show a poor clinical prognosis. Importantly, high RERG exp...
ORGANISM(S): Homo sapiens 
2005-07-23 | E-GEOD-2987 | biostudies-arrayexpress
UnknownHematotoxicity and Nephrotoxicity in Prostate Cancer Patients Undergoing Radioligand Therapy with [177Lu]Lu-PSMA I&T.
Not available
S-EPMC8833540 | biostudies-literature
UnknownBaseline clinical characteristics predict overall survival in patients undergoing radioligand therapy with [177Lu]Lu-PSMA I&T during long-term follow-up.
Not available
S-EPMC9525362 | biostudies-literature
UnknownEffect of delayed isolation of peripheral blood mononuclear cells on cell viability and functionality.
Not available
S-EPMC11909936 | biostudies-literature
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