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TranscriptomicsComparison of Genes in Imiquimod-treated and Control Tumors
The goal of the study is to examine changes in tumor gene expression after imiquimod treatment. RNA was extracted from spontaneous tumors in control mice (n=4) and in imiquimod-treated mice (n=4). Gene expression was compared between the control group and the treated group. In the imiquimod treat...
ORGANISM(S): Mus musculus 
2010-06-24 | E-GEOD-20032 | biostudies-arrayexpress
TranscriptomicsImiquimod treated Basal Cell Carcinoma
Imiquimod is a Toll-like receptor (TLR)-7 agonist capable of inducing complete clearance of basal cell carcinoma (BCC) and other cutaneous malignancies. We hypothesized that the characterization of the early transcriptional events induced by imiquimod may provide insights about immunological events ...
ORGANISM(S): Homo sapiens 
2006-10-04 | E-GEOD-5121 | biostudies-arrayexpress
TranscriptomicsMicroarray on cell populations sorted from the imiquimod-treated skin
The imiquimod model is used to induce the skin production of IL-22 and to characterize the cells that produce IL-22 in the skin after inflammatory stimulus. This experiment is performed on skin of C57Bl/6 mice treated with imiquimod to induce psoriasis-like lesions. After 5 days of imiquimod treatme...
ORGANISM(S): Mus musculus 
2016-08-09 | E-MTAB-4453 | biostudies-arrayexpress
ProteomicsTasmanian Devil Facial Tumour Disease - Imiquimod treatment of DFT1 cells
A Tasmanian Devil Facial Tumour Disease (DFTD) tumor cell line was treated with the drug Imiquimod
ORGANISM(S): Sarcophilus harrisii 
2018-04-12 | PXD007135 | Pride
Proteomics Imiquimod Dftd 
ProteomicsImiquimod in human CD8+ T cells
Blood CD8 T cells from six healthy blood donors were treated with the TLR7 agonist imiquimod + IL-2 in T cell enriched medium overnight in vitro (the controls were incubated with T cell enriched medium + IL-2 only). After approx. 21 h the in solution digest protocol was started.
ORGANISM(S): Homo sapiens (Human) 
2024-04-29 | PXD038621 | Pride
Imiquimod Cd8 t cells 
ProteomicsMDA5 signaling in splenic B cells from imiquimod-induced lupus mouse model with proteomics study
Abstract Introduction Several environmental stimuli may influence lupus, especially viral infection. We utilize an imiquimod-induced lupus mouse model focusing on TLR7 pathway and use proteomics analysis to figure out the specific pathway related to viral infection and its related protein expression...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD034855 | Pride
Mouse model B cell Imiquimod (imq) Proteomics Lupus Mda5 
TranscriptomicsStimulation of isolated plasmacytoid dendritic cells (pDCs) with TLR9 agonist CpG C (CpG) and TLR7 agonist imiquimod (IMQ)
The purpose of this experiment was to assess the genes upregulated when pDCs were stimulated with TLR7 agonist imiquimod and TLR9 agonist CpG C. pDCs were isolated from six healthy donors by FACS sorting, and were stimulated with CpG and imiquimod for 18 hours, after which RNA was extracted for next...
ORGANISM(S): Homo sapiens 
2016-03-17 | E-GEOD-79272 | biostudies-arrayexpress
GenomicsEffects of imiquimod on macrophages by transcriptomic analysis
Effects of imiquimod on macrophages by transcriptomic analysis
PRJNA1306094 | ENA
ProteomicsProteomic effects of budesonide and imiquimod on human bronchial epithelial cells
We carry out a comparative proteomic analysis of human bronchial epithelial cells from patients clinically treated or not with inhaled budesonide and stimulated or not with the viral mimic Poly(I:C).We also wanted to investigate the potential anti-viral effects of imiquimod, a TLR7 agonist, on the b...
ORGANISM(S): Homo sapiens (Human) 
2021-11-22 | PXD029135 | Pride
Huma Lung Bronchial epithelial cells Lc-ms/ms 
GenomicsExpression data from anisomycin- and imiquimod-induced dermatitis
Expression data from anisomycin- and imiquimod-induced dermatitis
PRJNA434204 | ENA
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