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TranscriptomicsComparison of miRNA expression profiling in CD14+ monocytes between anti-MDA5-positive three patients and three healthy controls
miRNA array was conducted to identify relevant pathological pathways in activated monocytes in anti-MDA5-positive patients in comparison of those in healthy controls.
ORGANISM(S): Homo sapiens 
2021-05-03 | E-MTAB-10471 | biostudies-arrayexpress
TranscriptomicsComparison of gene microarray analysis in CD14+ monocytes between anti-MDA5-positive three patients and three healthy controls
mRNA array was conducted to identify relevant pathological pathways in activated monocytes in anti-MDA5-positive patients in comparison of those in healthy controls.
ORGANISM(S): Homo sapiens 
2021-05-04 | E-MTAB-10472 | biostudies-arrayexpress
ProteomicsMDA5 signaling in splenic B cells from imiquimod-induced lupus mouse model with proteomics study
Abstract Introduction Several environmental stimuli may influence lupus, especially viral infection. We utilize an imiquimod-induced lupus mouse model focusing on TLR7 pathway and use proteomics analysis to figure out the specific pathway related to viral infection and its related protein expression...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD034855 | Pride
Mouse model B cell Imiquimod (imq) Proteomics Lupus Mda5 
GenomicsBreaching self-tolerance to Alu duplex RNA underlies MDA5-mediated inflammation [ADAR1KO HEK293T and WT MDA5]
Breaching self-tolerance to Alu duplex RNA underlies MDA5-mediated inflammation [ADAR1KO HEK293T and WT MDA5]
PRJNA414057 | ENA
ProteomicsLGP2 binds PACT to regulate RIG-I- and MDA5-mediated antiviral response
The RIG-I-like receptors (RLRs: RIG-I, MDA5 and LGP2) trigger inflammatory and antiviral responses by sensing non-self RNA molecules produced during viral replication. LGP2 regulation of RIG-I and MDA5-dependant type-I interferon signaling is a matter of controversy. Here we show that LGP2 interacts...
ORGANISM(S): Homo sapiens (Human) Mengo virus 
2019-10-02 | PXD013191 | Pride
Rig-1 Virus Rna silencing machinery Pact Lgp2 
GenomicsMDA5 guards against infection by surveying cellular RNA homeostasis [I]
MDA5 guards against infection by surveying cellular RNA homeostasis [I]
PRJNA869666 | ENA
GenomicsMDA5 guards against infection by surveying cellular RNA homeostasis [II]
MDA5 guards against infection by surveying cellular RNA homeostasis [II]
PRJNA886644 | ENA
GenomicsMDA5 regulates bleomycin-induced proinflammatory response of macrophages
MDA5 regulates bleomycin-induced proinflammatory response of macrophages
PRJNA1139705 | ENA
GenomicsRIG-I and MDA5 fRIP during KSHV lytic reactivation
RIG-I and MDA5 fRIP during KSHV lytic reactivation
PRJNA479810 | ENA
GenomicsChemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration
Chemotherapy-induced transposable elements activate MDA5 to enhance haematopoietic regeneration
PRJNA532340 | ENA
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