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TranscriptomicsTranscription profiling of testicular seminoma tumour stages (pT1, pT2, pT3) and 3 normal testes
Gene expression patterns of testicular seminoma were analysed applying oligonucleotide microarrays in 40 specimens of different tumour stages (pT1, pT2, pT3) and in 3 normal testes. Experiment Overall Design: A total of 40 pure seminoma including 22 samples of tumour stage 1 (pT1), 14 samples of tum...
ORGANISM(S): Homo sapiens 
2008-11-06 | E-GEOD-8607 | biostudies-arrayexpress
TranscriptomicsGenome-wide methylation analysis and gene expression profiling identifies genes silenced in non-seminoma cell lines [gene expression]
Germ cell tumours (GCTs) are a complex group of malignancies. They are unique in developing from a pluripotent progenitor cell. The initial lesion is believed to be the relatively benign precursor lesion (ICGNU), from which either highly chemosensitive seminomas or the more aggressive non-seminomas ...
ORGANISM(S): Homo sapiens 
2016-01-15 | E-GEOD-65026 | biostudies-arrayexpress
GenomicsSeminoma and embryonal carcinoma footprints identified by analysis of integrated genome-wide epigenetic and expression profiles of germ cell cancer cell lines (ChIP-seq data).
Background: Germ Cell Cancers (GCC), originating from Primordial Germ Cells /gonocytes, are the most common cancer in young men, subdivided in seminoma (SE) and non-seminoma (NS, stem cell component: embryonal carcinoma (EC)). Somatic mutations are rarely found in GCC. It has been proposed that disr...
ORGANISM(S): Homo sapiens 
2014-06-01 | E-GEOD-56450 | biostudies-arrayexpress
TranscriptomicsGenome-wide methylation analysis and gene expression profiling identifies genes silenced in non-seminoma cell lines [methylation]
Germ cell tumours (GCTs) are a complex group of malignancies. They are unique in developing from a pluripotent progenitor cell. The initial lesion is believed to be the relatively benign precursor lesion (ICGNU), from which either highly chemosensitive seminomas or the more aggressive non-seminomas ...
ORGANISM(S): Homo sapiens 
2016-01-15 | E-GEOD-65027 | biostudies-arrayexpress
ProteomicsDistinctive metabolic features of seminoma and embryonic carcinoma revealed by combined transcriptome and metabolomics analyses
Using well-characterized cell line models for seminoma (Tcam-2, n=15) and EC (NT2, n=15), we characterized their metabolite profiles using ultraperformance liquid chromatography coupled with Q-TOF mass spectrometry (UPLC/Q-TOF MS).
ORGANISM(S): Homo Sapiens 
2019-01-12 | PXD012313 |
TranscriptomicsGene expression analysis of human seminoma samples
Purpose: The aim of the present study was to examine the biological differences between seminomas with occult and clinically apparent metastases at the time of diagnosis of the primary tumor to gain insight into the biology of these tumors and facilitate the identification of novel predictors of sem...
ORGANISM(S): Homo sapiens 
2014-02-21 | E-GEOD-55198 | biostudies-arrayexpress
TranscriptomicsGenome-wide methylation analysis and gene expression profiling identifies genes silenced in non-seminoma cell lines
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-01-15 | E-GEOD-65028 | biostudies-arrayexpress
GenomicsGene expression analysis comparing between pure- and mixed type testicular seminoma
Gene expression analysis comparing between pure- and mixed type testicular seminoma
PRJNA704085 | ENA
GenomicsGenomic Screening of Testicular Germ Cell Tumors from Monozygotic Twins
Genomic screening was performed for one family containing MZ twins with testicular germ cell tumors, in order to define alterations associated with risk of tumor development. Copy number alterations were evaluated using array-CGH (4x44K, Agilent Technologies) in one seminoma and one embryonal carcin...
ORGANISM(S): Homo sapiens 
2015-01-31 | E-GEOD-62779 | biostudies-arrayexpress
UnknownContemporary surgical management of testicular seminoma.
Not available
S-EPMC11651731 | biostudies-literature
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