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ProteomicsmsSIM for single-cell proteomic analysis
We report the development of the spectral library-based multiplex segmented Selected Ion Monitoring (SLB-msSIM) method, a novel approach that significantly improves sensitivity and robustness for single-cell analysis. Single-cell MS data is acquired using the msSIM technique, which sequentially appl...
ORGANISM(S): Homo sapiens (Human) 
2025-10-13 | PXD055915 | Pride
Selected ion monitoring Single-cell proteomics Cancer cell heterogeneity 
ProteomicsGlyceraldehyde treatment on pancreatic ductal epithelial cells
To study the impact of the accumulation of glyceraldehyde-derived intracellular protein advanced glycation end products (AGEs) on global proteomic changes in pancreatic ductal epithelial cells. The cells were treated with glyceraldehyde for up to 2 days and changes of protein expressions were assess...
ORGANISM(S): Homo sapiens (Human) 
2025-07-21 | PXD050491 | Pride
Glycation Glyceraldehyde Advanced glcation end products (ages) Epethelial cells 
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