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TranscriptomicsTranscription profiling of mouse SCCVII murine cell line reveals irradiated stroma selects for invasive and metastatic tumoc cells
Radiotherapy is widely used to treat human cancer. Patients locally recurring after radiotherapy, however, have increased risk of metastatic progression and poor prognosis. The clinical management of post-radiation recurrences remains an unresolved issue. Tumors growing in pre-irradiated tissues hav...
ORGANISM(S): Mus musculus 
2009-05-11 | E-GEOD-11357 | biostudies-arrayexpress
TranscriptomicsTranscruption profiling of human cerebellum, frontal cortex [BA4, BA9] and caudate nucleus HD tissue experiment
Post mortem human brain tissue comparison between HD patients and controls from 3 brain regions - cerebellum, frontal cortex [BA4, BA9] and caudate nucleus. Gene expression analysed using linear models from LIMMA package in Bioconductor suite. Experiment Overall Design: Large sample sizes were used...
ORGANISM(S): Homo sapiens 
2009-09-12 | E-GEOD-3790 | biostudies-arrayexpress
TranscriptomicsEstablishment of objective criteria for selecting relevant intestinal cell-based models
The objective of this study was to make use of gene expression signatures and functional assays to delineate differences between various intestinal colon carcinoma cell lines and normal intestinal epithelium to assess their appropriateness as a tumor model or for drug absorption studies. [Cell lines...
ORGANISM(S): Homo sapiens 
2012-06-23 | E-GEOD-30292 | biostudies-arrayexpress
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