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The folate and methionine cycles (Met-C) are regulated by vitamin B12 (B12), obtained exclusively from diet and microbiota. Met-C supports amino acid, nucleotide, and lipid biosynthesis and provides one-carbon moieties for methylation reactions. While B12 deficiency and polymorphisms in Met-C gen...

2025-07-05 | MTBLS12457 | MetaboLights
Cell requires optimal amount of nutrients for the synthesis of macromolecules like lipid, protein and nucleotides. There is a very limited knowledge about how cells maintain homeostasis in excess nutrients. By using Yeast as a model system we have shown that some aminoacids are toxic at higher conce...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-08-13 | PXD014880 | Pride
Cell requires optimal amount of nutrients for the synthesis of macromolecules like lipid, protein and nucleotides. There is a very limited knowledge about how cells maintain homeostasis in excess nutrients. By using Yeast as a model system we have shown that some aminoacids are toxic at higher conce...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-08-13 | PXD014859 | Pride
We report the application of next generation sequencing technology for high-throughput profiling of cytosine methylation in adult rat liver tissue. To investigate the role of intragenic methylation, we generated the first high resolution methylation map of rat liver tissue and compared it with the p...
ORGANISM(S): Rattus norvegicus 
The transcriptomic response after 3 hours of DTT treatment shows there is not a drastic difference in most genes between WT and skn7∆, yap1∆ . Vma13∆, sse2∆ were also used as part of the study. Organism : Saccharomyces cerevisiae, Agilent Yeast Gene expression 8x15K Array AMADID: 016322
ORGANISM(S): Saccharomyces cerevisiae 
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