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Sensory innervation induced by osteoblast-derived netrin-4 attenuates bone loss in aged mice
The p75 neurotrophin receptor regulates the skeletal stem cell niche through sensory innervation
A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation [scRNA-seq]
The sensory denervation has a causal role in bone loss. The mechanism of bone cells regulation of sensory nerve wiring and sprouting for maintaining bone homeostasis remains unclear. Here we found that netrin-4, secreted by osteoblasts, facilitates the sprouting of sensory nerves through the DCC rec...
ORGANISM(S): Mus musculus 
2026-01-27 | GSE317225 | GEO
The cornea is the transparent tissue covering the anterior part of the eye. Its main roles are to convey the light toward the retina, and to act as a protective barrier against infection or injury for the eye. The transparency of the cornea is a crucial component of its functionality and is the resu...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD052337 | Pride
A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation [bulk RNA-seq]
Low bone mass is strongly associated with multiple neurologic diseases such as Alzheimer’s disease (AD), however it remains unclear if this represents direct specific biologic sequalae of the primary disease process or rather a non-specific finding attributable to alterations in behavior and activit...
ORGANISM(S): Mus musculus 
2025-08-27 | GSE263602 | GEO
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